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Genomic landscape of megakaryopoiesis and platelet function defectsVirally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cellsImpact of mutational status on outcomes in myelofibrosis patients treated with ruxolitinib in the COMFORT-II study.Co-culture of hematopoietic stem/progenitor cells with human osteblasts favours mono/macrophage differentiation at the expense of the erythroid lineage.MicroRNA expression profile in granulocytes from primary myelofibrosis patients.Proliferation, differentiation arrest, and survival in leukemic blast cells.Role of c-fes protooncogene in myeloid differentiation.Extracellular purines promote the differentiation of human bone marrow-derived mesenchymal stem cells to the osteogenic and adipogenic lineages.Eosinophils, but not neutrophils, exhibit an efficient DNA repair machinery and high nucleolar activity.Involvement of MAF/SPP1 axis in the development of bone marrow fibrosis in PMF patients.Targeted cancer exome sequencing reveals recurrent mutations in myeloproliferative neoplasms.MYB controls erythroid versus megakaryocyte lineage fate decision through the miR-486-3p-mediated downregulation of MAF.Development of an IL-6 antagonist peptide that induces apoptosis in 7TD1 cells.Induction of a functional vitamin D receptor in all-trans-retinoic acid-induced monocytic differentiation of M2-type leukemic blast cells.Inhibition of c-fes expression by an antisense oligomer causes apoptosis of HL60 cells induced to granulocytic differentiation.miRNA-mRNA integrative analysis in primary myelofibrosis CD34+ cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis.Expression and function of nerve growth factor and nerve growth factor receptor on cultured keratinocytes.Calreticulin mutation-specific immunostaining in myeloproliferative neoplasms: pathogenetic insight and diagnostic value.c-myb supports erythropoiesis through the transactivation of KLF1 and LMO2 expression.Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34- cell population with intrinsic resistance to imatinib.A functionally active RARalpha nuclear receptor is expressed in retinoic acid non responsive early myeloblastic cell lines.Requirement of the coiled-coil domains of p92(c-Fes) for nuclear localization in myeloid cells upon induction of differentiation.Bone marrow-derived hematopoietic cells undergo myogenic differentiation following a Pax-7 independent pathway.Valproic acid triggers erythro/megakaryocyte lineage decision through induction of GFI1B and MLLT3 expression.CALR mutational status identifies different disease subtypes of essential thrombocythemia showing distinct expression profiles.Physiological levels of 1alpha, 25 dihydroxyvitamin D3 induce the monocytic commitment of CD34+ hematopoietic progenitors.Molecular profiling of CD34+ cells in idiopathic myelofibrosis identifies a set of disease-associated genes and reveals the clinical significance of Wilms' tumor gene 1 (WT1).Isolation and characterization of a murine resident liver stem cell.Abnormal expression patterns of WT1-as, MEG3 and ANRIL long non-coding RNAs in CD34+ cells from patients with primary myelofibrosis and their clinical correlations.Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice.The extracellular nucleotide UTP is a potent inducer of hematopoietic stem cell migrationThe number of prognostically detrimental mutations and prognosis in primary myelofibrosis: an international study of 797 patientsRole of TGF-β1/miR-382-5p/SOD2 axis in the induction of oxidative stress in CD34+ cells from primary myelofibrosisBone marrow-specific loss of induces myeloproliferative neoplasm with features resembling human myelofibrosisAbundance of the primary transcript and its processed product of growth-related genes in normal and leukemic cells during proliferation and differentiationDetection of low abundance mRNA of myeloid specific genes in cells of acute and chronic lymphoid leukemias by cRNA hybridization[Mitochondrial DNA deletion in a case of progressive ophthalmoplegia][Expression of lactoferrin and myeloperoxidase genes in blasts of acute lymphoblastic leukemia][Possible correlations between proliferation and differentiation of blast cells in acute promyelocytic leukemia: a molecular study]Differential effects of c-myb and c-fes antisense oligodeoxynucleotides on granulocytic differentiation of human myeloid leukemia HL60 cells
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0003-0660-6110
@en
name
Rossella Manfredini
@ast
Rossella Manfredini
@en
Rossella Manfredini
@es
Rossella Manfredini
@nl
type
label
Rossella Manfredini
@ast
Rossella Manfredini
@en
Rossella Manfredini
@es
Rossella Manfredini
@nl
prefLabel
Rossella Manfredini
@ast
Rossella Manfredini
@en
Rossella Manfredini
@es
Rossella Manfredini
@nl
P106
P1153
7005646810
P31
P496
0000-0003-0660-6110