Inhibition of c-fes expression by an antisense oligomer causes apoptosis of HL60 cells induced to granulocytic differentiation.
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A point mutation in the N-terminal coiled-coil domain releases c-Fes tyrosine kinase activity and survival signaling in myeloid leukemia cellsInhibition of calmodulin-dependent phosphodiesterase induces apoptosis in human leukemic cellsThe cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors.The Fes protein-tyrosine kinase phosphorylates a subset of macrophage proteins that are involved in cell adhesion and cell-cell signalingControl of myeloid differentiation and survival by Stats.Activated Fes protein tyrosine kinase induces terminal macrophage differentiation of myeloid progenitors (U937 cells) and activation of the transcription factor PU.1.Phospholipase D2 (PLD2) shortens the time required for myeloid leukemic cell differentiation: mechanism of actionThe myeloid-cell-specific c-fes promoter is regulated by Sp1, PU.1, and a novel transcription factor.Identification of a molecular signature predictive of sensitivity to differentiation induction in acute myeloid leukemia.Apoptosis: regulation and relevance to toxicology.Fes tyrosine kinase promotes survival and terminal granulocyte differentiation of factor-dependent myeloid progenitors (32D) and activates lineage-specific transcription factors.The nonreceptor protein-tyrosine kinase c-Fes is involved in fibroblast growth factor-2-induced chemotaxis of murine brain capillary endothelial cells.Activation of STAT3 by the c-Fes protein-tyrosine kinase.Lyn and Fgr protein-tyrosine kinases prevent apoptosis during retinoic acid-induced granulocytic differentiation of HL-60 cells.Phosphorylation of a Fes-related protein in response to granulocyte-macrophage colony stimulating factor.Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils.A functionally active RARalpha nuclear receptor is expressed in retinoic acid non responsive early myeloblastic cell lines.Requirement of the coiled-coil domains of p92(c-Fes) for nuclear localization in myeloid cells upon induction of differentiation.
P2860
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P2860
Inhibition of c-fes expression by an antisense oligomer causes apoptosis of HL60 cells induced to granulocytic differentiation.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Inhibition of c-fes expression ...... granulocytic differentiation.
@en
type
label
Inhibition of c-fes expression ...... granulocytic differentiation.
@en
prefLabel
Inhibition of c-fes expression ...... granulocytic differentiation.
@en
P2093
P2860
P356
P1476
Inhibition of c-fes expression ...... o granulocytic differentiation
@en
P2093
C Franceschi
D Barbieri
E Tagliafico
P Zucchini
P2860
P304
P356
10.1084/JEM.178.2.381
P407
P577
1993-08-01T00:00:00Z