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The Reverse Transcriptase Encoded by LINE-1 Retrotransposons in the Genesis, Progression, and Therapy of CancerA reverse transcriptase-dependent mechanism is essential for murine preimplantation developmentSpecific localization of transcription factors in the chromatin of mouse mature spermatozoa.Endogenous reverse transcriptase as a mediator of ursolic acid's anti-proliferative and differentiating effects in human cancer cell lines.Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformationHERV-K activation is strictly required to sustain CD133+ melanoma cells with stemness features.Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase.Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors.Distinct roles for LINE-1 and HERV-K retroelements in cell proliferation, differentiation and tumor progression.Inhibition of endogenous reverse transcriptase antagonizes human tumor growth.Role of endogenous reverse transcriptase in murine early embryo development.Generation of biologically active retro-genes upon interaction of mouse spermatozoa with exogenous DNA.Sperm endogenous reverse transcriptase as mediator of new genetic information.Mouse early embryos obtained by natural breeding or in vitro fertilization display a differential sensitivity to extremely low-frequency electromagnetic fields
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description
researcher ORCID ID = 0000-0002-5629-6184
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wetenschapper
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name
Ilaria Sciamanna
@ast
Ilaria Sciamanna
@en
Ilaria Sciamanna
@es
Ilaria Sciamanna
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type
label
Ilaria Sciamanna
@ast
Ilaria Sciamanna
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Ilaria Sciamanna
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Ilaria Sciamanna
@nl
prefLabel
Ilaria Sciamanna
@ast
Ilaria Sciamanna
@en
Ilaria Sciamanna
@es
Ilaria Sciamanna
@nl
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P1153
6507522925
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0000-0002-5629-6184