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Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 InhibitorsFragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAPMonoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based DiscoveryExploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment ScreeningSynthesis of the thapsigarginsFragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2).Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2Structure-Activity and Structure-Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1/NRF2) Protein-Protein Interaction
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description
researcher ORCID ID = 0000-0002-6453-5819
@en
wetenschapper
@nl
name
Alison J-A Woolford
@ast
Alison J-A Woolford
@en
Alison J-A Woolford
@es
Alison J-A Woolford
@nl
type
label
Alison J-A Woolford
@ast
Alison J-A Woolford
@en
Alison J-A Woolford
@es
Alison J-A Woolford
@nl
prefLabel
Alison J-A Woolford
@ast
Alison J-A Woolford
@en
Alison J-A Woolford
@es
Alison J-A Woolford
@nl
P106
P31
P496
0000-0002-6453-5819