Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells
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Ligand-, cell-, and estrogen receptor subtype (alpha/beta)-dependent activation at GC-rich (Sp1) promoter elementsThe structural basis of androgen receptor activation: intramolecular and intermolecular amino-carboxy interactionsPhosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistanceFull activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cellsInteraction of estrogen receptor alpha with 3-methyladenine DNA glycosylase modulates transcription and DNA repairHuman estrogen receptor beta binds DNA in a manner similar to and dimerizes with estrogen receptor alphaThe N-terminal regions of estrogen receptor alpha and beta are unstructured in vitro and show different TBP binding propertiesMetabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma.Activation function 2 (AF2) of estrogen receptor-alpha is required for the atheroprotective action of estradiol but not to accelerate endothelial healing.Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes.The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor alphaThe role of activation functions 1 and 2 of estrogen receptor-α for the effects of estradiol and selective estrogen receptor modulators in male miceEffects of estrogens and endocrine-disrupting chemicals on cell differentiation-survival-proliferation in brain: contributions of neuronal cell lines.Carcinogenic mechanisms of endometrial cancer: involvement of genetics and epigenetics.Analysis of mechanisms that determine dominant negative estrogen receptor effectiveness.Unique protein determinants of the subtype-selective ligand responses of the estrogen receptors (ERalpha and ERbeta ) at AP-1 sites.CRISPR/Cas9-mediated targeting of the Rosa26 locus produces Cre reporter rat strains for monitoring Cre/loxP-mediated lineage tracing.The relative contribution exerted by AF-1 and AF-2 transactivation functions in estrogen receptor alpha transcriptional activity depends upon the differentiation stage of the cell.The tamoxifen-responsive estrogen receptor alpha mutant D351Y shows reduced tamoxifen-dependent interaction with corepressor complexes.Inhibition of cell migration by 24-kDa fibroblast growth factor-2 is dependent upon the estrogen receptor.Estrogen response elements can mediate agonist activity of anti-estrogens in human endometrial Ishikawa cells.Estrogen receptor-KRAB chimeras are potent ligand-dependent repressors of estrogen-regulated gene expression.MAP kinase/estrogen receptor cross-talk enhances estrogen-mediated signaling and tumor growth but does not confer tamoxifen resistance.Phosphorylation of human estrogen receptor alpha at serine 118 by two distinct signal transduction pathways revealed by phosphorylation-specific antisera.Mutual repression of transcriptional activation between the ETS-related factor ERG and estrogen receptor.Molecular mechanism of estrogen-estrogen receptor signaling.Nuclear and Membrane Actions of Estrogen Receptor Alpha: Contribution to the Regulation of Energy and Glucose Homeostasis.Yeast two-hybrid detection systems that are highly sensitive to a certain kind of endocrine disruptors.p300 Mediates Functional Synergism between AF-1 and AF-2 of Estrogen Receptor α and β by Interacting Directly with the N-terminal A/B Domains
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P2860
Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im April 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
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wetenschappelijk artikel
@nl
наукова стаття, опублікована у квітні 1995
@uk
name
Characterization of the Amino- ...... ptor in Animal and Yeast Cells
@en
Characterization of the Amino- ...... ptor in Animal and Yeast Cells
@nl
type
label
Characterization of the Amino- ...... ptor in Animal and Yeast Cells
@en
Characterization of the Amino- ...... ptor in Animal and Yeast Cells
@nl
prefLabel
Characterization of the Amino- ...... ptor in Animal and Yeast Cells
@en
Characterization of the Amino- ...... ptor in Animal and Yeast Cells
@nl
P2093
P2860
P356
P1476
Characterization of the amino- ...... ptor in animal and yeast cells
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P2093
P2860
P304
P356
10.1074/JBC.270.16.9535
P407
P577
1995-04-01T00:00:00Z