The specific innate immune receptor CEACAM3 triggers neutrophil bactericidal activities via a Syk kinase-dependent pathway
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Rho GTPases as pathogen targets: Focus on curable sexually transmitted infectionsThe adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteriaGlobal analysis of neutrophil responses to Neisseria gonorrhoeae reveals a self-propagating inflammatory programCoevolution of activating and inhibitory receptors within mammalian carcinoembryonic antigen familiesOpa+ Neisseria gonorrhoeae exhibits reduced survival in human neutrophils via Src family kinase-mediated bacterial trafficking into mature phagolysosomesPhase-Variable Heptose I Glycan Extensions Modulate Efficacy of 2C7 Vaccine Antibody Directed against Neisseria gonorrhoeae Lipooligosaccharide.Neisseria gonorrhoeae elicits extracellular traps in primary neutrophil culture while suppressing the oxidative burst.Assembly of NADPH oxidase in human neutrophils is modulated by the opacity-associated protein expression State of Neisseria gonorrhoeaeConstitutively Opa-expressing and Opa-deficient neisseria gonorrhoeae strains differentially stimulate and survive exposure to human neutrophilsA bacterial siren song: intimate interactions between Neisseria and neutrophils.Loss of mammal-specific tectorial membrane component carcinoembryonic antigen cell adhesion molecule 16 (CEACAM16) leads to hearing impairment at low and high frequencies.Fluorescence resonance energy transfer (FRET)-based subcellular visualization of pathogen-induced host receptor signaling.Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classification.Mediators of Tyrosine Phosphorylation in Innate Immunity: From Host Defense to Inflammation onto Oncogenesis.Selection for a CEACAM receptor-specific binding phenotype during Neisseria gonorrhoeae infection of the human genital tract.The SYK tyrosine kinase: a crucial player in diverse biological functions.The innate immune response to Salmonella enterica serovar Typhimurium by macrophages is dependent on TREM2-DAP12Innate recognition by neutrophil granulocytes differs between Neisseria gonorrhoeae strains causing local or disseminating infections.CLEC-2 is a phagocytic activation receptor expressed on murine peripheral blood neutrophils.Opa proteins and CEACAMs: pathways of immune engagement for pathogenic Neisseria.Moraxella catarrhalis: from interactions with the host immune system to vaccine development.Defining the roles of human carcinoembryonic antigen-related cellular adhesion molecules during neutrophil responses to Neisseria gonorrhoeae.Bcl10 synergistically links CEACAM3 and TLR-dependent inflammatory signalling.Gonococcal lipooligosaccharide sialylation: virulence factor and target for novel immunotherapeutics.Moraxella catarrhalis induces CEACAM3-Syk-CARD9-dependent activation of human granulocytes.A carcinoembryonic antigen-related cell adhesion molecule 1 homologue plays a pivotal role in nontypeable Haemophilus influenzae colonization of the chinchilla nasopharynx via the outer membrane protein P5-homologous adhesin.Phosphatidylinositol 3'-kinase activity is critical for initiating the oxidative burst and bacterial destruction during CEACAM3-mediated phagocytosis.Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract: neutrophilic host response, sustained infection, and clinical sequelae.Specific binding to differentially-expressed human CEACAMs determines the outcome of Neisseria gonorrhoeae infections along the female reproductive tract.
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P2860
The specific innate immune receptor CEACAM3 triggers neutrophil bactericidal activities via a Syk kinase-dependent pathway
description
im September 2007 veröffentlichter wissenschaftlicher Artikel
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scientific article published on 15 May 2007
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wetenschappelijk artikel
@nl
наукова стаття, опублікована у вересні 2007
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name
The specific innate immune rec ...... a Syk kinase-dependent pathway
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The specific innate immune rec ...... a Syk kinase-dependent pathway
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type
label
The specific innate immune rec ...... a Syk kinase-dependent pathway
@en
The specific innate immune rec ...... a Syk kinase-dependent pathway
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prefLabel
The specific innate immune rec ...... a Syk kinase-dependent pathway
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The specific innate immune rec ...... a Syk kinase-dependent pathway
@nl
P1476
The specific innate immune rec ...... a Syk kinase-dependent pathway
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P2093
Helen Sarantis
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P304
P356
10.1111/J.1462-5822.2007.00947.X
P577
2007-05-15T00:00:00Z