Thrombin Stimulates Phosphorylation of Insulin-like Growth Factor-1 Receptor, Insulin Receptor Substrate-1, and Phospholipase C-γ1 in Rat Aortic Smooth Muscle Cells
about
Src-family tyrosine kinases in activation of ERK-1 and p85/p110-phosphatidylinositol 3-kinase by G/CCKB receptorsA role for chemokine receptor transactivation in growth factor signaling.Thrombin induces expression of FGF-2 via activation of PI3K-Akt-Fra-1 signaling axis leading to DNA synthesis and motility in vascular smooth muscle cellsSrc phosphorylates the insulin-like growth factor type I receptor on the autophosphorylation sites. Requirement for transformation by src.Activation of Trk neurotrophin receptors in the absence of neurotrophinsSomething old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationInsulin-like growth factor-1 receptor transactivation modulates the inflammatory and proliferative responses of neurotensin in human colonic epithelial cells.Engagement of β-arrestin by transactivated insulin-like growth factor receptor is needed for V2 vasopressin receptor-stimulated ERK1/2 activation.Phospholipase Cgamma activation and phosphoinositide hydrolysis are essential for embryonal developmentRoles of proteolysis in regulation of GPCR function.Inhibition of VCAM-1 expression on mouse vascular smooth muscle cells by lobastin via downregulation of p38, ERK 1/2 and NF-κB signaling pathways.Ramalin inhibits VCAM-1 expression and adhesion of monocyte to vascular smooth muscle cells through MAPK and PADI4-dependent NF-kB and AP-1 pathways.Sphingosine 1-phosphate transactivates c-Met as well as epidermal growth factor receptor (EGFR) in human gastric cancer cells.alpha-thrombin rapidly induces tyrosine phosphorylation of a novel, 74-78-kDa stress response protein(s) in lung fibroblast cells.Reactive oxygen species mediate Met receptor transactivation by G protein-coupled receptors and the epidermal growth factor receptor in human carcinoma cells.Lysophosphatidic acid inhibits Ca2+ signaling in response to epidermal growth factor receptor stimulation in human astrocytoma cells by a mechanism involving phospholipase C(gamma) and a G(alphai) protein.Eicosanoid activation of extracellular signal-regulated kinase1/2 in human epidermoid carcinoma cells.RNA sequencing to determine the contribution of kinase receptor transactivation to G protein coupled receptor signalling in vascular smooth muscle cells.Angiotensin II-induced association of phospholipase Cgamma1 with the G-protein-coupled AT1 receptor.Mutations at residues Tyr771 and Tyr783 of phospholipase C-gamma1 have different effects on cell actin-cytoskeleton organization and cell proliferation in CCL-39 cells.Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase.Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases.Tumor necrosis factor alpha inhibits insulin-induced mitogenic signaling in vascular smooth muscle cells.SRC family kinases mediate epithelial Na+ channel inhibition by endothelin.Thrombin regulates vascular smooth muscle cell growth and heat shock proteins via the JAK-STAT pathway.Beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis.Not so strange bedfellows: G-protein-coupled receptors and Src family kinases.STAT-3-dependent cytosolic phospholipase A2 expression is required for thrombin-induced vascular smooth muscle cell motility.IGF-1 promotes angiogenesis in endothelial cells/adipose-derived stem cells co-culture system with activation of PI3K/Akt signal pathway.Elevated levels of the IGF-binding protein protease MMP-1 in asthmatic airway smooth muscle.Cannabinoid 1 receptor-dependent transactivation of fibroblast growth factor receptor 1 emanates from lipid rafts and amplifies extracellular signal-regulated kinase 1/2 activation in embryonic cortical neurons.
P2860
Q22010243-81F3EFE4-0C1A-4ED4-9F77-1A2FE78365B9Q28360845-1A99CEE7-BA60-4AAE-A327-014624F8E4D2Q28581725-68CD4E03-EAF1-4A34-B8C3-49BF5D16B77FQ30469710-9E32F2AD-E110-4002-9616-6BE471FFAA07Q33937877-41D30FA3-B59F-4EEA-8B52-A199F7296384Q34387886-BDB6C76C-5FEF-43A9-B4B8-257A84C2DC36Q34676029-331A24E9-3E9C-4529-80AC-A20168914AE3Q35921791-5A8FA895-E608-4698-A429-88835EA66355Q36152346-746BDD07-6BC8-468B-B47F-F56A55B50EE3Q38050189-B2EFB0A5-D9BB-42B1-815B-0E9D30703CD9Q38817422-634BEEAF-C39F-443F-AF29-F607546CC72EQ38930168-49714DFA-67E1-4D08-B3D9-49D0CFBD1840Q40489621-778A6160-2FA7-4F44-8CDA-FB6632BFBF39Q40516121-CC53A96A-3C32-4D9E-A54F-C1066D57AD16Q40559771-60791780-8F2C-48DD-82B8-0E1428989156Q40855100-7D1BA703-C61C-4BBE-89CB-90B6A4BED92CQ40859818-DE000792-E5DB-4015-9CC6-AE52B61B6767Q41047719-1F7C61CD-775F-4975-9642-E13D886A4ECAQ41049990-E1F6721C-F108-47B3-B796-3586A65B54C7Q41059475-CC743CFC-6911-46D1-B532-2DE28BA08D3AQ41066099-EEB4C48E-F380-4BE5-AD9E-4D05C480D3F0Q41175767-0A9A0AB6-7F06-45B7-98A4-518960153406Q41730147-5552182E-8FE1-4A3D-8F8B-6624A869F154Q42510249-EF552EBD-F311-471C-853C-CA2B0F48D458Q43559449-394014F7-C4A1-4079-8EEA-ECE0B7BD5836Q44610984-ACE45B13-40E1-4391-A2D4-7FEAB6272178Q45111099-C9471E6A-4142-4A4E-B2F3-AD07E6994898Q45153426-2C750C77-26C2-4D3D-9EA7-C9F2729BDD0BQ47727030-4A7D26C2-B03F-4964-94C6-E7470163EB33Q50336343-4D9D7475-6C58-4FA4-95B1-390BD9B80116Q54621645-71844373-CEF2-48B5-A465-EFB9C8A70E39
P2860
Thrombin Stimulates Phosphorylation of Insulin-like Growth Factor-1 Receptor, Insulin Receptor Substrate-1, and Phospholipase C-γ1 in Rat Aortic Smooth Muscle Cells
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im November 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в листопаді 1995
@uk
name
Thrombin Stimulates Phosphoryl ...... Rat Aortic Smooth Muscle Cells
@en
Thrombin Stimulates Phosphoryl ...... Rat Aortic Smooth Muscle Cells
@nl
type
label
Thrombin Stimulates Phosphoryl ...... Rat Aortic Smooth Muscle Cells
@en
Thrombin Stimulates Phosphoryl ...... Rat Aortic Smooth Muscle Cells
@nl
prefLabel
Thrombin Stimulates Phosphoryl ...... Rat Aortic Smooth Muscle Cells
@en
Thrombin Stimulates Phosphoryl ...... Rat Aortic Smooth Muscle Cells
@nl
P2860
P356
P1476
Thrombin stimulates phosphoryl ...... rat aortic smooth muscle cells
@en
P2093
P2860
P304
27871-27875
P356
10.1074/JBC.270.46.27871
P407
P577
1995-11-01T00:00:00Z