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DNA-programmed spatial screening of carbohydrate–lectin interactions

DNA-programmed spatial screening of carbohydrate–lectin interactions

http://www.wikidata.org/entity/Q58001611

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DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes.DNA display of PNA-tagged ligands: a versatile strategy to screen libraries and control geometry of multidentate ligands Expanding the scope of PNA-encoded synthesis (PES): Mtt-protected PNA fully orthogonal to fmoc chemistry and a broad array of robust diversity-generating reactions.PNA-encoded synthesis (PES) of a 10 000-member hetero-glycoconjugate library and microarray analysis of diverse lectins.DNA-Encoded Dynamic Combinatorial Chemical Libraries.DNA-guided display of proteins and protein ligands for the interrogation of biology.Multivalency as a chemical organization and action principle.Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications.Bridging lectin binding sites by multivalent carbohydrates.Carbohydrate-PNA and aptamer-PNA conjugates for the spatial screening of lectins and lectin assemblies.Double-clicking peptides onto phosphorothioate oligonucleotides: combining two proapoptotic agents in one molecule.Probing heterobivalent binding to the endocytic AP-2 adaptor complex by DNA-based spatial screening.Design, preparation, and selection of DNA-encoded dynamic libraries Directed evolution of 2G12-targeted nonamannose glycoclusters by SELMA.Regulation of an enzyme cascade reaction by a DNA machine.Defined presentation of carbohydrates on a duplex DNA scaffold.Dynamic Cooperative Glycan Assembly Blocks the Binding of Bacterial Lectins to Epithelial Cells.Efficient Buchwald-Hartwig-Migita Cross-Coupling for DNA Thioglycoconjugation.Searching for avidity by chemical ligation of combinatorially self-assembled DNA-encoded ligand libraries.DNA-controlled bivalent presentation of ligands for the estrogen receptor.Picture perfect: DNA-templated photoaffinity labeling.Detection of bond formations by DNA-programmed chemical reactions and PCR amplification.DNA glycoclusters and DNA-based carbohydrate microarrays: From design to applications Reversible blocking of antibodies using bivalent peptide–DNA conjugates allows protease-activatable targeting

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DNA-programmed spatial screening of carbohydrate–lectin interactions

http://www.wikidata.org/entity/Q58001611

description

im Januar 2011 veröffentlichter wissenschaftlicher Artikel

@de

wetenschappelijk artikel

@nl

наукова стаття, опублікована у 2011

@uk

name

DNA-programmed spatial screening of carbohydrate–lectin interactions

@en

DNA-programmed spatial screening of carbohydrate–lectin interactions

@nl

type

label

DNA-programmed spatial screening of carbohydrate–lectin interactions

@en

DNA-programmed spatial screening of carbohydrate–lectin interactions

@nl

prefLabel

DNA-programmed spatial screening of carbohydrate–lectin interactions

@en

DNA-programmed spatial screening of carbohydrate–lectin interactions

@nl

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Chemical Science

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DNA-programmed spatial screening of carbohydrate–lectin interactions

@en

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Alexander Bujotzek

http://www.w3.org/2001/XMLSchema#string

Christian Scheibe

http://www.w3.org/2001/XMLSchema#string

Jens Dernedde

http://www.w3.org/2001/XMLSchema#string

Marcus Weber

http://www.w3.org/2001/XMLSchema#string

P2860

Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands

Structural basis of multivalent binding to wheat germ agglutinin

Solution structure of a peptide nucleic acid-DNA duplex

The cluster glycoside effect.

Multivalent protein-carbohydrate interactions. A new paradigm for supermolecular assembly and signal transduction.

Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide.

DNA-templated homo- and heterodimerization of peptide nucleic acid encoded oligosaccharides that mimick the carbohydrate epitope of HIV.

Analysis of specific interactions of synthetic glycopolypeptides carrying N-acetyllactosamine and related compounds with lectins.

Crystal structures of Erythrina cristagalli lectin with bound N-linked oligosaccharide and lactose.

Optimization of tether length in nonglycosidically linked bivalent ligands that target sites 2 and 1 of a Shiga-like toxin.

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770

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scholarly article

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10.1039/C0SC00565G

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4

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2

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2011-01-01T00:00:00Z

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