Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis
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EPHA2 is associated with age-related cortical cataract in mice and humansA novel connexin 50 (GJA8) mutation in a Chinese family with a dominant congenital pulverulent nuclear cataract.Beta-1 integrin is important for the structural maintenance and homeostasis of differentiating fiber cells.Homeostasis in the vertebrate lens: mechanisms of solute exchange.Molecular analysis of cataract families in India: new mutations in the CRYBB2 and GJA3 genes and rare polymorphisms.Connexin46fs380 causes progressive cataracts.Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2.A novel GJA8 mutation (p.V44A) causing autosomal dominant congenital cataract.Lens gap junctions in growth, differentiation, and homeostasis.Focus on lens connexins.The unfolded protein response is activated in connexin 50 mutant mouse lenses.Sporadic and Familial Congenital Cataracts: Mutational Spectrum and New Diagnoses Using Next-Generation Sequencing.A novel connexin 50 gene (gap junction protein, alpha 8) mutation associated with congenital nuclear and zonular pulverulent cataract.Connexin mutation that causes dominant congenital cataracts inhibits gap junctions, but not hemichannels, in a dominant negative mannerInteraction between Connexin50 and mitogen-activated protein kinase signaling in lens homeostasis.Connexin50D47A decreases levels of fiber cell connexins and impairs lens fiber cell differentiation.Functional effects of Cx50 mutations associated with congenital cataracts.Roles and regulation of lens epithelial cell connexins.The role of Connexin 46 promoter in lens and other hypoxic tissues.The cataract causing Cx50-S50P mutant inhibits Cx43 and intercellular communication in the lens epithelium.
P2860
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P2860
Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis
description
article
@en
im April 2006 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована у квітні 2006
@uk
name
Diverse gap junctions modulate ...... velopment and cataractogenesis
@en
Diverse gap junctions modulate ...... velopment and cataractogenesis
@nl
type
label
Diverse gap junctions modulate ...... velopment and cataractogenesis
@en
Diverse gap junctions modulate ...... velopment and cataractogenesis
@nl
prefLabel
Diverse gap junctions modulate ...... velopment and cataractogenesis
@en
Diverse gap junctions modulate ...... velopment and cataractogenesis
@nl
P2093
P356
P1433
P1476
Diverse gap junctions modulate ...... velopment and cataractogenesis
@en
P2093
Bruce Beutler
Catherine Cheng
Chun-Hong Xia
Debra Cheung
Haiquan Liu
Woo-Kuen Lo
Xiaohua Gong
P304
P356
10.1242/DEV.02361
P407
P50
P577
2006-04-12T00:00:00Z