about
FURIN; PACE4Membrane profilaggrin processing proteasesSubtilisin/kexin-like convertaseFURIN;PCSK6Cleavage of the viral Env gp160 precursor polyproteinFurin cleaves ANTXR1-bound PA83 to yield PA63Furin cleaves ANTXR2-bound PA83 to yield PA63Fibrillin C-terminal processingActivation of proMMP11 by FURINActivation of MT-MMPs by FURINCollagen type XXIII ectodomain sheddingCollagen type XXV ectomain sheddingFurin cleaves pro-factor IX to factor IXFurin cleaves pro-factor VII to factor VIIFurin cleaves pro-factor X to factor XFurin cleaves pro-prothrombin to prothrombinFurin cleaves pro-protein C to protein CFurin cleaves pro-protein S to protein SFurin cleaves pro-protein Z to protein ZFurin cleaves pro-GAS6 to GAS6Furin cleaves pro-BGLAP to BGLAPFURIN cleaves 7K-BACE1 to 7K-BACE1(46-501)PDGF-AA clevage by FurinPDGF-BB clevage by FurinPDGF-AB clevage by FurinLatent TGF-beta-1 is cleaved by furinNOTCH precursor cleaved to form mature NOTCHFringe-modified Pre-NOTCH is cleaved by FURIN
P527
P688
Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementiaThe prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivityFurin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasisThe proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A: functional consequences of natural mutations and post-translational modificationsHuman carcinoma cell growth and invasiveness is impaired by the propeptide of the ubiquitous proprotein convertase furinThe shedding activity of ADAM17 is sequestered in lipid raftsProprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi networkCell-surface processing of pro-ADAMTS9 by furinProcessing of prothyrotropin-releasing hormone by the family of prohormone convertasesIdentification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell linesDifferential processing of proenkephalin by prohormone convertases 1(3) and 2 and furinBeta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furinCellular processing of the nerve growth factor precursor by the mammalian pro-protein convertasesCargo-selective endosomal sorting for retrieval to the Golgi requires retromerProcessing of transforming growth factor beta 1 precursor by human furin convertaseActivation of the furin endoprotease is a multiple-step process: requirements for acidification and internal propeptide cleavageThe ordered and compartment-specfific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation.Processing of pro-B-type natriuretic peptide: furin and corin as candidate convertases.Glycosylation and processing of pro-B-type natriuretic peptide in cardiomyocytes.Cell entry mechanisms of SARS-CoV-2
P921
Q50255043-228372D9-D3DB-45D9-AC43-15EB8FC82BC9Q50255347-3EDBD7E8-BDD1-4A52-B2D3-844300AE6D3DQ50271186-3AAE6CC8-0157-4358-82FC-9A4A8EE41C79Q50274730-B4061B34-82DB-484D-8C1E-E8F3F494C970Q50289393-D5C1E94C-162F-432C-92CE-BA67CD06572AQ50289622-7E959395-8116-4071-9C8D-155AAC6CD107Q50289623-DDD8721E-8F5D-4796-85AB-377C85E02907Q50289804-B9ED3D8D-A9A7-4360-B35B-0FF639AAAB0BQ50289917-935A6562-92CB-4E16-A93A-884E6E15A26BQ50289922-D783676F-AEDB-4935-92B1-76A407C8C4D3Q50289958-B8B5ABCA-8AB9-4205-A477-3ED73B8F5EB1Q50289959-130DFF6E-6DB7-4CFE-8F4F-4202189E4B9AQ50296142-20B6A3C9-0E5E-4719-9938-7C74EA8FCFD4Q50296143-2B9AC231-0833-43E5-9F88-1BD6D0778B22Q50296144-44DF948E-3A35-47CB-82F9-34051610FF54Q50296145-46652607-08EA-4E9C-A18A-E43D7288DDDAQ50296146-4E79F401-A50A-4CD9-8BDE-7E14A63211E5Q50296147-7FBC434F-9737-4FA5-BBBC-C25F505892F3Q50296148-8DCE2916-1B2D-43BD-97D5-1B61CAD99FF4Q50296149-C3941187-57FD-42A9-8895-3C0715234B72Q50296150-3E375695-B292-4340-A4D0-9D976ED2A042Q50296936-4D693BB4-047A-47D9-9301-343CFB7B486FQ50297828-3C6E0110-838F-4584-BD33-69C214FDA9D3Q50297829-731A0F51-C836-4475-B3CE-10C716D09AB4Q50297830-5749B630-3E57-4C6D-83B8-E221BD3332C4Q50298151-6162A480-2433-48F6-A980-8EA01EC4A812Q50298612-002828B3-FB07-41C0-B6C4-A6F3D86D0ECFQ50298616-5F9BD92E-2D54-446E-BD4E-A64C9EB30091
P527
Q22010692-6496607C-A2DC-4969-AC96-AD65D611BB72Q22010813-1BE1B4CB-2ADB-4F98-BCF1-0E47152DBD4FQ24297889-BA687BCE-71A5-43F4-8960-5BDF816291A1Q24299848-DC526516-9F95-4A19-9270-3280BFEC8BE1Q24302360-D45506E9-CF6E-4E05-927B-43DCB1AA6D52Q24305222-2996CAB3-567A-4D46-87A1-FC1E748418DAQ24306398-A8E24393-6812-49C9-9C81-8677B1D686ADQ24307820-2B4EB59A-62B1-409C-A9B5-2E5990D0A196Q24320347-27FF2FFD-E26E-4E9C-B3D9-3723A779FC31Q24322611-04AF1FDB-3C98-4F59-8D7F-AC827DBEDAF4Q24322816-40FD4AF1-E995-48BF-AFFF-D13D6D72952EQ24323262-63F33F8D-6EBB-4A81-90DD-4C7FE4320394Q24336205-78C2E444-4A40-487B-B2D9-D2BFD30907AAQ24336448-5AD642E8-7E25-45A8-9358-E33A81515A70Q28300881-81FCA387-85FE-465F-9AE5-A8A4EB312732Q28941774-E1DD290B-65AE-47AE-B032-EE266B48A3A8Q28941778-0B7E310A-CDF9-4E3F-B196-0DB9B4AD9B7DQ34116710-AFBD2646-74EA-455D-85A2-447A3D5F81ABQ35154172-E7D36DDA-3B91-4FED-9FB6-9B4F1C375017Q94589965-41436b73-4bbc-3d4a-529f-8e3b6a7e34fb
P921
description
enzima
@it
enzyme
@fr
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
بروتين بشري
@ar
name
Furin
@sh
Furin
@sr
Furin, paired basic amino acid cleaving enzyme
@en
Furin, paired basic amino acid cleaving enzyme
@nl
Furina
@it
Furine
@fr
Фурин
@ru
フーリン
@ja
type
label
Furin
@sh
Furin
@sr
Furin, paired basic amino acid cleaving enzyme
@en
Furin, paired basic amino acid cleaving enzyme
@nl
Furina
@it
Furine
@fr
Фурин
@ru
フーリン
@ja
altLabel
Dibasic-processing enzyme
@en
FES upstream region
@en
FURIN
@en
FURIN/ADAMTS1 fusion
@en
PACE
@en
dibasic processing enzyme
@en
furin, membrane associated receptor protein
@en
paired basic amino acid residue-cleaving enzyme
@en
proprotein convertase subtilisin/kexin type 3
@en
prefLabel
Furin
@sh
Furin
@sr
Furin, paired basic amino acid cleaving enzyme
@en
Furin, paired basic amino acid cleaving enzyme
@nl
Furina
@it
Furine
@fr
Фурин
@ru
フーリン
@ja
P361
P527
P637
P638
P680
P681
P682
P705
P352
P486
P646
P2888
P31
P352
P361
P486
P527
P637
NP_001276752
NP_001276753
NP_001369548
NP_001369549
NP_001369550
NP_001369551
P638
P646
P680
P681
P682
P702
P703
P705
ENSP00000268171
ENSP00000452730
ENSP00000453212
ENSP00000453942
ENSP00000483552
ENSP00000484952
ENSP00000491453