Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways
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Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinomaRegulation of Bim in Health and DiseaseMolecular profiling reveals diversity of stress signal transduction cascades in highly penetrant Alzheimer's disease human skin fibroblastsFoxO3a is activated and executes neuron death via Bim in response to β-amyloidNerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of BimCbl negatively regulates JNK activation and cell deathRole and regulation of Cdc25A phosphatase in neuron death induced by NGF deprivation or β-amyloidEpstein-barr virus latency in B cells leads to epigenetic repression and CpG methylation of the tumour suppressor gene BimGenetic control of programmed cell death during animal development.Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult.Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim.The essential role of p53-up-regulated modulator of apoptosis (Puma) and its regulation by FoxO3a transcription factor in β-amyloid-induced neuron death.AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis.PGE₂ promotes apoptosis induced by cytokine deprivation through EP3 receptor and induces Bim in mouse mast cells.Bcl-2 antagonists interact synergistically with bortezomib in DLBCL cells in association with JNK activation and induction of ER stress.Differential roles of Epac in regulating cell death in neuronal and myocardial cells.Kallistatin attenuates endothelial apoptosis through inhibition of oxidative stress and activation of Akt-eNOS signaling.Hsp27 binding to the 3'UTR of bim mRNA prevents neuronal death during oxidative stress-induced injury: a novel cytoprotective mechanism.The co-repressor SMRT delays DNA damage-induced caspase activation by repressing pro-apoptotic genes and modulating the dynamics of checkpoint kinase 2 activation.Cell signaling underlying epileptic behavior.Granulocyte/macrophage colony-stimulating factor causes a paradoxical increase in the BH3-only pro-apoptotic protein Bim in human neutrophils.Bim and Bmf in tissue homeostasis and malignant disease.A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer.Overexpression of Batf induces an apoptotic defect and an associated lymphoproliferative disorder in mice.Curcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease through suppressing mitochondria dysfunction.A Drosophila gain-of-function screen for candidate genes involved in steroid-dependent neuroendocrine cell remodelingPin1 promotes cell death in NGF-dependent neurons through a mechanism requiring c-Jun activity.Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death.Programmed cell death during neuronal development: the sympathetic neuron model.Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM.Increased expression of c-Fos by extracellular signal-regulated kinase activation under sustained oxidative stress elicits BimEL upregulation and hepatocyte apoptosis.Bim gene dosage is critical in modulating nephron progenitor survival in the absence of microRNAs during kidney development.MiR-124 Regulates Apoptosis and Autophagy Process in MPTP Model of Parkinson's Disease by Targeting to Bim.Erg and AP-1 as determinants of glucocorticoid response in acute lymphoblastic leukemia.Glucocorticoid-mediated BIM induction and apoptosis are regulated by Runx2 and c-Jun in leukemia cells.18β-glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF-7 cells.Targeting the regulatory machinery of BIM for cancer therapy.Glucocorticoid-induced leucine zipper (GILZ) promotes the nuclear exclusion of FOXO3 in a Crm1-dependent manner.Neuroprotective effects of phenolic antioxidant tBHQ associate with inhibition of FoxO3a nuclear translocation and activityModeling the Mechanism of GR/c-Jun/Erg Crosstalk in Apoptosis of Acute Lymphoblastic Leukemia.
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Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im August 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
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wetenschappelijk artikel
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наукова стаття, опублікована в серпні 2007
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name
Pro-apoptotic Bim Induction in ...... erent Death Signaling Pathways
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Pro-apoptotic Bim Induction in ...... erent Death Signaling Pathways
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type
label
Pro-apoptotic Bim Induction in ...... erent Death Signaling Pathways
@en
Pro-apoptotic Bim Induction in ...... erent Death Signaling Pathways
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prefLabel
Pro-apoptotic Bim Induction in ...... erent Death Signaling Pathways
@en
Pro-apoptotic Bim Induction in ...... erent Death Signaling Pathways
@nl
P2093
P2860
P356
P1476
Pro-apoptotic Bim induction in ...... erent death signaling pathways
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P2093
Lloyd A Greene
Subhas C Biswas
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P304
29368-29374
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10.1074/JBC.M702634200
P407
P577
2007-08-16T00:00:00Z