about
Diurnal variation in the quantitative EEG in healthy adult volunteersElectroencephalographic and psychomotor effects of chlorpromazine and risperidone relative to placebo in normal healthy volunteersA pilot study to explore circulating tumour cells in pancreatic cancer as a novel biomarker.Circulating tumor cells as a window on metastasis biology in lung cancer.An investigation of components of variance and tachyphylaxis in a placebo-controlled intravenous tyramine studyEffect of oral linezolid on the pressor response to intravenous tyramine.Specific inhibition of the endothelin A receptor with ZD4054: clinical and pre-clinical evidence.Assessing proliferation, cell-cycle arrest and apoptotic end points in human buccal punch biopsies for use as pharmacodynamic biomarkers in drug development.Evaluation of circulating tumor cells and serological cell death biomarkers in small cell lung cancer patients undergoing chemotherapyAnalytical validation of BRAF mutation testing from circulating free DNA using the amplification refractory mutation testing system.Detection of PIK3CA mutations in circulating free DNA in patients with breast cancer.Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study.Assessment of the reproducibility of intradermal administration of capsaicin as a model for inducing human pain.Biomarker utility of circulating tumor cells in metastatic cutaneous melanoma.Preclinical evaluation of M30 and M65 ELISAs as biomarkers of drug induced tumor cell death and antitumor activity.The prostaglandin E2 receptor-1 (EP-1) mediates acid-induced visceral pain hypersensitivity in humans.Quantitative multiplexed quantum dot immunohistochemistry.Assessment of diurnal changes and confounding factors that affect circulating cell death biomarker levels: a short communication.Considerations for powering a clinical proteomics study: Normal variability in the human plasma proteome.Oxytocin in the central nervous system and sexual behaviour in male rats.Multiplexed assays for detection of mutations in PIK3CA.Prevalence and heterogeneity of circulating tumour cells in metastatic cutaneous melanomaQuantification of skeletal metastases in castrate-resistant prostate cancer predicts progression-free and overall survivalA Pilot Study Assessing the Prognostic Value of CK18 and nDNA Biomarkers in Severe Sepsis PatientsAnalysis of Circulating Tumor Cells in Patients with Non-small Cell Lung Cancer Using Epithelial Marker-Dependent and -Independent ApproachesEvaluation and Prognostic Significance of Circulating Tumor Cells in Patients With Non–Small-Cell Lung CancerIsolation and Extraction of Circulating Tumor DNA from Patients with Small Cell Lung CancerA first-in-man phase I tolerability and pharmacokinetic study of the cyclin-dependent kinase-inhibitor AZD5438 in healthy male volunteersA phase I pharmacodynamic study of the effects of the cyclin-dependent kinase-inhibitor AZD5438 on cell cycle markers within the buccal mucosa, plucked scalp hairs and peripheral blood mononucleocytes of healthy male volunteersSerum biomarkers of apoptosisAbsolute quantification of farnesylated Ras levels in complex samples using liquid chromatography fractionation combined with tryptic digestion and electrospray tandem mass spectrometryStaged Risk Management of Candidate Drug EfficacyMetabonomics, dietary influences and cultural differences: a 1H NMR-based study of urine samples obtained from healthy British and Swedish subjectsNovel approaches in oncology at AstraZenecaEffects of Zolmitriptan (ZomigTM) on Central Serotonergic Neurotransmission as Assessed by Active Oddball Auditory Event-Related Potentials in Volunteers without Migraine
P50
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P50
description
researcher, ORCID id # 0000-0002-8690-4056
@en
wetenschapper
@nl
name
Andrew Hughes
@ast
Andrew Hughes
@en
Andrew Hughes
@es
Andrew Hughes
@nl
type
label
Andrew Hughes
@ast
Andrew Hughes
@en
Andrew Hughes
@es
Andrew Hughes
@nl
prefLabel
Andrew Hughes
@ast
Andrew Hughes
@en
Andrew Hughes
@es
Andrew Hughes
@nl
P106
P1153
7401766183
P21
P31
P496
0000-0002-8690-4056