Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses
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An overview of Cdk1-controlled targets and processesThe FHIT gene product: tumor suppressor and genome "caretaker"A genetic screen for increased loss of heterozygosity in Saccharomyces cerevisiae.Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution.Condensin suppresses recombination and regulates double-strand break processing at the repetitive ribosomal DNA array to ensure proper chromosome segregation during meiosis in budding yeast.Initiation of genome instability and preneoplastic processes through loss of Fhit expressionA dynamic stochastic model for DNA replication initiation in early embryosThe relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation.Global regulation of genome duplication in eukaryotes: an overview from the epifluorescence microscope.Essential global role of CDC14 in DNA synthesis revealed by chromosome underreplication unrecognized by checkpoints in cdc14 mutants.Structural maintenance of chromosomes (SMC) proteins promote homolog-independent recombination repair in meiosis crucial for germ cell genomic stability.The DNA damage response pathway contributes to the stability of chromosome III derivatives lacking efficient replicators.Rtt107 phosphorylation promotes localisation to DNA double-stranded breaks (DSBs) and recombinational repair between sister chromatids.The Smc5-Smc6 complex is required to remove chromosome junctions in meiosis.The maintenance of chromosome structure: positioning and functioning of SMC complexes.The Smc5-Smc6 complex regulates recombination at centromeric regions and affects kinetochore protein sumoylation during normal growth.Rescue from replication stress during mitosis.Restriction of replication fork regression activities by a conserved SMC complex.Roles of vertebrate Smc5 in sister chromatid cohesion and homologous recombinational repair.Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier.The chromosomal association of the Smc5/6 complex depends on cohesion and predicts the level of sister chromatid entanglement.Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres.The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structuresNSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activityRegulation of rtt107 recruitment to stalled DNA replication forks by the cullin rtt101 and the rtt109 acetyltransferase.Sequential steps in DNA replication are inhibited to ensure reduction of ploidy in meiosis.Cell cycle regulation of DNA replication.Smc5-Smc6 complex suppresses gross chromosomal rearrangements mediated by break-induced replications.Chromatin state marks cell-type- and gender-specific replication of the Drosophila genome.Unreplicated DNA in mitosis precludes condensin binding and chromosome condensation in S. cerevisiae.The (elusive) role of the SMC5/6 complexReplication intermediates that escape Dna2 activity are processed by Holliday junction resolvase Yen1.Incision of damaged DNA in the presence of an impaired Smc5/6 complex imperils genome stabilitySmc5/6-mediated regulation of replication progression contributes to chromosome assembly during mitosis in human cells.DNA replication and spindle checkpoints cooperate during S phase to delay mitosis and preserve genome integrityPerspectives on the DNA damage and replication checkpoint responses in Saccharomyces cerevisiae.The SMC complexes, DNA and chromosome topology: right or knot?Cdc14 phosphatase: warning, no delay allowed for chromosome segregation!Meiotic Recombination: The Essence of Heredity.Transcription-replication conflicts at chromosomal fragile sites-consequences in M phase and beyond.
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Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses
description
article publié dans la revue scientifique Science
@fr
im März 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Science
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в березні 2007
@uk
name
Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses
@en
Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses
@nl
type
label
Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses
@en
Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses
@nl
prefLabel
Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses
@en
Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses
@nl
P2093
P50
P356
P1433
P1476
Anaphase onset before complete DNA replication with intact checkpoint responses
@en
P2093
Adam Jarmuz
Felix Machin
Giacomo De Piccoli
Luis Aragón
Sarah Farmer
Violeta Cordon-Preciado
P304
P356
10.1126/SCIENCE.1134025
P407
P577
2007-03-01T00:00:00Z