about
What does the concept of the stem cell niche really mean today?Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell FunctionStem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic LeukemiaLeukemogenic rearrangements at the mixed lineage leukemia gene (MLL)-multiple rather than a single mechanismTargeting the molecular and cellular interactions of the bone marrow niche in immunologic diseaseAdipose tissue as a potential source of hematopoietic stem/progenitor cellsRenal stem cells: fact or science fiction?Drosophila E-cadherin functions in hematopoietic progenitors to maintain multipotency and block differentiationKindlin-3-mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells.Donor hematopoietic stem cells confer long-term marrow reconstitution by self-renewal divisions exceeding to that of host cellsConcise review: The plasticity of stem cell niches: a general property behind tissue homeostasis and repair.One more stem cell niche: how the sensitivity of chronic myeloid leukemia cells to imatinib mesylate is modulated within a "hypoxic" environment.Tumor cell dormancyTherapy-related myeloid neoplasms: pathobiology and clinical characteristicsSustained proliferation in cancer: Mechanisms and novel therapeutic targetsParathyroid hormone administration improves bone marrow microenvironment and partially rescues haematopoietic defects in Bmi1-null miceCDK6 as a key regulator of hematopoietic and leukemic stem cell activationModel Based Analysis of Clonal Developments Allows for Early Detection of Monoclonal Conversion and LeukemiaDynamic variation in cycling of hematopoietic stem cells in steady state and inflammationHuman extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironmentAcute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiationImproved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B.Exonuclease 1 is a critical mediator of survival during DNA double strand break repair in nonquiescent hematopoietic stem and progenitor cells.Tissue inhibitor of metalloproteinase-3 (TIMP-3) regulates hematopoiesis and bone formation in vivo.Extended time-lapse in vivo imaging of tibia bone marrow to visualize dynamic hematopoietic stem cell engraftment.Cytokine-regulated GADD45G induces differentiation and lineage selection in hematopoietic stem cells.ERK1 regulates the hematopoietic stem cell nichesDetection of dormant chronic myeloid leukemia clones in the bone marrow of patients in complete molecular remission.Requirement for ssbp2 in hematopoietic stem cell maintenance and stress responseDistinct clinical phenotypes associated with JAK2V617F reflect differential STAT1 signalingReactive oxygen species in normal and tumor stem cells.Relevance of the mevalonate biosynthetic pathway in the regulation of bone marrow mesenchymal stromal cell-mediated effects on T-cell proliferation and B-cell survivalTranscriptome-wide profiling and posttranscriptional analysis of hematopoietic stem/progenitor cell differentiation toward myeloid commitmentLifespan differences in hematopoietic stem cells are due to imperfect repair and unstable mean-reversionContractile forces sustain and polarize hematopoiesis from stem and progenitor cells.Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescenceHematopoietic stem cell quiescence and function are controlled by the CYLD-TRAF2-p38MAPK pathway.BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia.hCD2-iCre and Vav-iCre mediated gene recombination patterns in murine hematopoietic cells.The haematopoietic stem cell niche at a glance.
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P2860
description
im März 2010 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в березні 2010
@uk
name
Awakening dormant haematopoietic stem cells
@en
Awakening dormant haematopoietic stem cells
@nl
type
label
Awakening dormant haematopoietic stem cells
@en
Awakening dormant haematopoietic stem cells
@nl
prefLabel
Awakening dormant haematopoietic stem cells
@en
Awakening dormant haematopoietic stem cells
@nl
P356
P1476
Awakening dormant haematopoietic stem cells
@en
P2093
Anne Wilson
P304
P356
10.1038/NRI2726
P577
2010-03-01T00:00:00Z