Mutation of E2F2 in Mice Causes Enhanced T Lymphocyte Proliferation, Leading to the Development of Autoimmunity
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Targeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor ImmunityThe E2F2 transcription factor sustains hepatic glycerophospholipid homeostasis in miceA role for E2F activities in determining the fate of Myc-induced lymphomagenesisThe DP-1 transcription factor is required for keratinocyte growth and epidermal stratificationCanonical and atypical E2Fs regulate the mammalian endocycleRepression by RB1 characterizes genes involved in the penultimate stage of erythroid developmentContrasting roles of E2F2 and E2F3 in cardiac neovascularization.Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphismsHER2/Neu tumorigenesis and metastasis is regulated by E2F activator transcription factors.Roles of salivary components in Streptococcus mutans colonization in a new animal model using NOD/SCID.e2f1-/- miceDifferential proteomics analysis reveals a role for E2F2 in the regulation of the Ahr pathway in T lymphocytes.E2f1-3 are critical for myeloid development.Emerging roles of E2Fs in cancer: an exit from cell cycle controlCell-cycle regulation of T-cell responses--novel approaches to the control of alloimmunity.Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesisE2F1 and E2F2 prevent replicative stress and subsequent p53-dependent organ involution.Lmo2 induces hematopoietic stem cell-like features in T-cell progenitor cells prior to leukemiaK48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression.Immunotherapeutic targets in estrogen deficiency-dependent Sjögren's syndrome-related manifestations.Interleukin-6 induces expression of Ifi202, an interferon-inducible candidate gene for lupus susceptibility.A role for transcription factor E2F2 in hepatocyte proliferation and timely liver regeneration.Network-based analysis of differentially expressed genes in cerebrospinal fluid (CSF) and blood reveals new candidate genes for multiple sclerosis.Molecular Profile of Tumor-Specific CD8+ T Cell Hypofunction in a Transplantable Murine Cancer Model.The nuclear protein ALY binds to and modulates the activity of transcription factor E2F2.E2F2 and CREB cooperatively regulate transcriptional activity of cell cycle genes.Rescued tolerant CD8 T cells are preprogrammed to reestablish the tolerant state.Survivin repression by p53, Rb and E2F2 in normal human melanocytes.E2F-1-deficient NOD/SCID mice developed showing decreased saliva production.Role of gene E2f1 in susceptibility to bacterial adherence of oral streptococci to tooth surfaces in mice.High incidence of thymic epithelial tumors in E2F2 transgenic mice.CD151 Expression Is Associated with a Hyperproliferative T Cell Phenotype.Innate immune response gene expression profiles characterize primary antiphospholipid syndrome.Transcriptional Regulation by CpG Sites Methylation in the Core Promoter Region of the Bovine SIX1 Gene: Roles of Histone H4 and E2F2.Accelerated DNA replication in E2F1- and E2F2-deficient macrophages leads to induction of the DNA damage response and p21(CIP1)-dependent senescence.The combined effect of BCL-2 over-expression and E2F2 deficiency induces an autoimmune syndrome in non-susceptible mouse strain C57BL/6.Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2
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Mutation of E2F2 in Mice Causes Enhanced T Lymphocyte Proliferation, Leading to the Development of Autoimmunity
description
article
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im Dezember 2001 veröffentlichter wissenschaftlicher Artikel
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wetenschappelijk artikel
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наукова стаття, опублікована в грудні 2001
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name
Mutation of E2F2 in Mice Cause ...... he Development of Autoimmunity
@en
Mutation of E2F2 in Mice Cause ...... he Development of Autoimmunity
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type
label
Mutation of E2F2 in Mice Cause ...... he Development of Autoimmunity
@en
Mutation of E2F2 in Mice Cause ...... he Development of Autoimmunity
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prefLabel
Mutation of E2F2 in Mice Cause ...... he Development of Autoimmunity
@en
Mutation of E2F2 in Mice Cause ...... he Development of Autoimmunity
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P2093
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P1433
P1476
Mutation of E2F2 in mice cause ...... he development of autoimmunity
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P2093
L R Borlado
M E Greenberg
Y Fujiwara
P304
P356
10.1016/S1074-7613(01)00254-0
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P577
2001-12-01T00:00:00Z