Survivin repression by p53, Rb and E2F2 in normal human melanocytes.
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The transcription factor p53: not a repressor, solely an activatorRal GTPase down-regulation stabilizes and reactivates p53 to inhibit malignant transformationDihydromyricetin Induces Apoptosis and Reverses Drug Resistance in Ovarian Cancer Cells by p53-mediated Downregulation of Survivin1,1-Bis(3'-indolyl)-1-(p-bromophenyl)methane and related compounds repress survivin and decrease gamma-radiation-induced survivin in colon and pancreatic cancer cellsYin Yang 1 regulates the transcriptional repression of SurvivinTargeting Hsp90 with small molecule inhibitors induces the over-expression of the anti-apoptotic molecule, survivin, in human A549, HONE-1 and HT-29 cancer cells.P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferationPro-proliferative FoxM1 is a target of p53-mediated repression.Aberrant activation of ERK/FOXM1 signaling cascade triggers the cell migration/invasion in ovarian cancer cells.Differential proteomics analysis reveals a role for E2F2 in the regulation of the Ahr pathway in T lymphocytes.Survivin is a therapeutic target in Merkel cell carcinoma.The p16(INK4A) tumor suppressor regulates cellular oxidative stressA natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells.Insulin Protects Cardiac Myocytes from Doxorubicin Toxicity by Sp1-Mediated Transactivation of SurvivinAurora B kinase phosphorylates and instigates degradation of p53Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradationRelation between expression pattern of p53 and survivin in cutaneous basal cell carcinomas.Familial melanoma-associated mutations in p16 uncouple its tumor-suppressor functionsEpithelial PIK3R1 (p85) and TP53 Regulate Survivin Expression during Adaptation to Ileocecal Resection.Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers.Gene expression profiling of paraffin-embedded primary melanoma using the DASL assay identifies increased osteopontin expression as predictive of reduced relapse-free survival.Arsenic trioxide induces apoptosis in B-cell chronic lymphocytic leukemic cells through down-regulation of survivin via the p53-dependent signaling pathway.One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor.Survivin in skin pathologies.The impact of age on oncogenic potential: tumor-initiating cells and the brain microenvironment.Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex.RB1 dual role in proliferation and apoptosis: cell fate control and implications for cancer therapy.Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease.Census and evaluation of p53 target genes.Decitabine and SAHA-induced apoptosis is accompanied by survivin downregulation and potentiated by ATRA in p53-deficient cells.Depletion of K-Ras promotes proteasome degradation of survivinSurvivin enhances motility of melanoma cells by supporting Akt activation and {alpha}5 integrin upregulation.Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase.Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus (KSHV) upregulates survivin expression in KSHV-Associated B-lymphoma cells and contributes to their proliferation.Human T-cell lymphotropic virus type 1 infection of CD34+ hematopoietic progenitor cells induces cell cycle arrest by modulation of p21(cip1/waf1) and survivin.Expression of cell cycle regulatory factors hus1, gadd45a, rb1, cdkn2a and mre11a correlates with expression of clock gene per2 in human colorectal carcinoma tissue.Epigenetic mechanism of survivin dysregulation in human cancer.HDAC2 and HDAC5 Up-Regulations Modulate Survivin and miR-125a-5p Expressions and Promote Hormone Therapy Resistance in Estrogen Receptor Positive Breast Cancer Cells.Inhibition of survivin expression after using oxaliplatin and vinflunine to induce cytogenetic damage in vitro in lymphocytes from colon cancer patients and healthy individuals.Yin Yang 1 (YY1): Regulation of Survivin and Its Role In Invasion and Metastasis.
P2860
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P2860
Survivin repression by p53, Rb and E2F2 in normal human melanocytes.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Survivin repression by p53, Rb and E2F2 in normal human melanocytes.
@en
Survivin repression by p53, Rb and E2F2 in normal human melanocytes.
@nl
type
label
Survivin repression by p53, Rb and E2F2 in normal human melanocytes.
@en
Survivin repression by p53, Rb and E2F2 in normal human melanocytes.
@nl
prefLabel
Survivin repression by p53, Rb and E2F2 in normal human melanocytes.
@en
Survivin repression by p53, Rb and E2F2 in normal human melanocytes.
@nl
P2093
P2860
P356
P1433
P1476
Survivin repression by p53, Rb and E2F2 in normal human melanocytes.
@en
P2093
Deepak Raj
Douglas Grossman
Fengzhi Li
George Samadashwily
P2860
P304
P356
10.1093/CARCIN/BGM219
P407
P577
2007-10-04T00:00:00Z