Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas
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In vitro selection of mutant HDM2 resistant to Nutlin inhibitionThe splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA.Identification of novel gene targets and functions of p21-activated kinase 1 during DNA damage by gene expression profilingStress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct waysp53 -Dependent and -Independent Nucleolar Stress Responses.Endogenous human MDM2-C is highly expressed in human cancers and functions as a p53-independent growth activator.A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo.Among 45 variants in 11 genes, HDM2 promoter polymorphisms emerge as new candidate biomarker associated with radiation toxicity.In vitro and in silico studies of MDM2/MDMX isoforms predict Nutlin-3A sensitivity in well/de-differentiated liposarcomas.
P2860
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P2860
Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas
description
article
@en
im Juni 2001 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована у 2001
@uk
name
Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas
@en
Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas
@nl
type
label
Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas
@en
Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas
@nl
prefLabel
Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas
@en
Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas
@nl
P2093
P2860
P356
P1476
Analysis of the molecular species generated by MDM2 gene amplification in liposarcomas
@en
P2093
A Azzarelli
C Lavarino
G Della Torre
P Carpinelli
P2860
P304
P356
10.1002/IJC.1271
P577
2001-06-01T00:00:00Z