Synthesis and Pharmacological Evaluation of α4β2Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus

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Synthesis and Pharmacological Evaluation of α4β2Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus

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im April 2015 veröffentlichter wissenschaftlicher Artikel

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scientific article published on 16 April 2015

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wetenschappelijk artikel

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наукова стаття, опублікована у квітні 2015

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Synthesis and Pharmacological ...... a 3-Fluoropyrrolidine Nucleus

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Synthesis and Pharmacological ...... a 3-Fluoropyrrolidine Nucleus

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Synthesis and Pharmacological ...... a 3-Fluoropyrrolidine Nucleus

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Synthesis and Pharmacological ...... a 3-Fluoropyrrolidine Nucleus

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Synthesis and Pharmacological ...... a 3-Fluoropyrrolidine Nucleus

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Synthesis and Pharmacological ...... a 3-Fluoropyrrolidine Nucleus

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Synthesis and Pharmacological ...... a 3-Fluoropyrrolidine Nucleus

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Cecilia Gotti

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Francesca Fasoli

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P2860

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Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 2. Prediction of blood-brain barrier penetration.

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Medicinal chemical properties of successful central nervous system drugs

In silico predictions of blood-brain barrier penetration: considerations to "keep in mind".

Synthesis and evaluation of 3-¹²³I-iodo-5-[2-(S)-3-pyrrolinylmethoxy]-pyridine (niodene) as a potential nicotinic α4β2 receptor imaging agent.

Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors.

P304

1071-1078

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P31

scholarly article

P356

10.1002/CMDC.201500073

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P433

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P478

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P577

2015-04-16T00:00:00Z

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25882435

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P921

Farmakologi