M1 muscarinic cetylcholine receptor allosteric modulators as potential therapeutic opportunities for treating Alzheimer's disease

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Molecular alliance-from orthosteric and allosteric ligands to dualsteric/bitopic agonists at G protein coupled receptors.A Photoswitchable Dualsteric Ligand Controlling Receptor Efficacy.Bitopic muscarinic agonists and antagonists and uses thereof: a patent evaluation of US20160136145A1.

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M1 muscarinic cetylcholine receptor allosteric modulators as potential therapeutic opportunities for treating Alzheimer's disease

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http://www.wikidata.org/entity/Q58856223

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im Januar 2012 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована у 2012

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M1 muscarinic cetylcholine rec ...... r treating Alzheimer's disease

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M1 muscarinic cetylcholine rec ...... r treating Alzheimer's disease

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M1 muscarinic cetylcholine rec ...... r treating Alzheimer's disease

@en

M1 muscarinic cetylcholine rec ...... r treating Alzheimer's disease

@nl

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M1 muscarinic cetylcholine rec ...... r treating Alzheimer's disease

@en

M1 muscarinic cetylcholine rec ...... r treating Alzheimer's disease

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M1 muscarinic cetylcholine rec ...... r treating Alzheimer's disease

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Michael Decker

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Functional Selectivity and Classical Concepts of Quantitative Pharmacology

Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders

Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: development of a potent and highly selective M1 PAM

Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1

A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning

Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity.

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease

Muscarinic agonists for the treatment of cognition in schizophrenia

Discovery and characterization of novel subtype-selective allosteric agonists for the investigation of M(1) receptor function in the central nervous system.

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752

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scholarly article

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10.1039/C2MD20025B

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http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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Ulrike Holzgrabe

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2012-01-01T00:00:00Z

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M1 muscarinic cetylcholine receptor allosteric modulators as potential therapeutic opportunities for treating Alzheimer's disease

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M1 muscarinic cetylcholine receptor allosteric modulators as potential therapeutic opportunities for treating Alzheimer's disease

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P1476

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P356

P433

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P577

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P1476

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