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The effect of mobile phase composition in the enantioseparation of pharmaceutically relevant compounds with polysaccharide-based stationary phases.Determination of bile salt critical micellization concentration on the road to drug discovery.S-trityl-(R)-cysteine, a multipurpose chiral selector for ligand-exchange liquid chromatography applications.Chiral ligand-exchange separation and resolution of extremely rigid glutamate analogs: 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids.Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity.Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: role of the chirality on the biological activity.Synthesis and quantitative structure-property relationships of side chain-modified hyodeoxycholic acid derivatives.Preparative resolution of 1-aminoindan-1,5-dicarboxylic acid (AIDA) by chiral ligand-exchange chromatography.Ketoprofen enantioseparation with a Cinchona alkaloid based stationary phase: enantiorecognition mechanism and release studies.The effect of the copper(II) salt anion in the Chiral Ligand-Exchange Chromatography of amino acids.Direct HPLC separation of carnosine enantiomers with two chiral stationaryn phases based on penicillamine and teicoplanin derivatives.Achiral-chiral two-dimensional chromatography of free amino acids in milk: A promising tool for detecting different levels of mastitis in cows.Enantioresolution and stereochemical characterization of two chiral sulfoxides endowed with COX-2 inhibitory activity.Descriptive structure-separation relationship studies in chiral ligand-exchange chromatography.Cysteine-based chiral selectors for the ligand-exchange separation of amino acids.Simultaneous diastereo- and enantioseparation of farnesoid X receptor (FXR) agonists with a quinine carbamate-based chiral stationary phase.Enantioselective HPLC of potentially CNS-active acidic amino acids with a Cinchona carbamate based chiral stationary phase.Novel orthogonal liquid chromatography methods to dose neurotransmitters involved in Parkinson's disease.Direct chromatographic enantioresolution of fully constrained β-amino acids: exploring the use of high-molecular weight chiral selectors.Chiral separation of helical chromenes with chloromethyl phenylcarbamate polysaccharide-based stationary phases.GC-MS/MS detects potential pregabalin abuse in susceptible subjects' hair.(S)-(-)-alpha,alpha-Di(2-naphthyl)-2-pyrrolidinemethanol, a useful tool to study the recognition mechanism in chiral ligand-exchange chromatography.Assessment of safety and efficiency of nitrogen organic fertilizers from animal-based protein hydrolysates--a laboratory multidisciplinary approach.Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel openerHydrophobic Amino Acid Content in Onions as Potential Fingerprints of Geographical Origin: The Case ofGlucuronidation of bile acids under flow conditions: design of experiments and Koenigs-Knorr reaction optimizationUse of an o-Benzyl-(S)-Serine Containing Eluent for the Efficient Ligand-Exchange Chromatography-Based Enantioseparation of Constrained Glutamate Receptor LigandsDiastereo- and enantioseparation of a Nα-Boc amino acid with a zwitterionic quinine-based stationary phase: Focus on the stereorecognition mechanismCombined monodimensional chromatographic approaches to monitor the presence of d-amino acids in cheesePyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonistsSynthesis and chromatographic resolution of conformationally constrained analogues of homotaurineEvaluation of the enantiomeric selectivity in the chiral ligand-exchange chromatography of amino acids by a computational modelSynthesis and chromatographic enantioresolution of anti-HIV quinolone derivativesOnion ( L.) Skin: A Rich Resource of Biomolecules for the Sustainable Production of Colored Biofunctional TextilesCorrelation between CMC and chromatographic index: simple and effective evaluation of the hydrophobic/hydrophilic balance of bile acidsComputational studies for the elucidation of the enantiomer elution order of amino acids in chiral ligand-exchange chromatographyNovel stereoselective synthesis and chromatographic evaluation of E-guggulsteroneDerived chromatographic indices as effective tools to study the self-aggregation process of bile acidsDynamic ligand-exchange chiral stationary phase from S-benzyl-(R)-cysteineContinuous flow synthesis and scale-up of glycine- and taurine-conjugated bile salts
P50
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P50
description
researcher ORCID ID = 0000-0001-9856-0230
@en
wetenschapper
@nl
name
Roccaldo Sardella
@ast
Roccaldo Sardella
@en
Roccaldo Sardella
@es
Roccaldo Sardella
@nl
type
label
Roccaldo Sardella
@ast
Roccaldo Sardella
@en
Roccaldo Sardella
@es
Roccaldo Sardella
@nl
prefLabel
Roccaldo Sardella
@ast
Roccaldo Sardella
@en
Roccaldo Sardella
@es
Roccaldo Sardella
@nl
P106
P1153
23669291700
P31
P496
0000-0001-9856-0230