about
K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology.Potent antiobesity effect of a short-length peptide YY-analogue continuously administered in mice.Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging.Metastin and its variant forms suppress migration of pancreatic cancer cells.Diastereoselective synthesis of new psi[(E)-CH=CMe]- and psi[(Z)-CH=CMe]-type alkene dipeptide isosteres by organocopper reagents and application to conformationally restricted cyclic RGD peptidomimetics.Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity.Crystal Structure of a Human K-Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d.Antiobesity and emetic effects of a short-length peptide YY analog and its PEGylated and alkylated derivatives.Highly potent antiobesity effect of a short-length peptide YY analog in mice.Structure-activity relationship study on small peptidic GPR54 agonists.Antiobesity Effect of a Short-Length Peptide YY Analogue after Continuous Administration in Mice.A Short-Length Peptide YY Analogue with Anorectic Effect in Mice.Fmoc-based solid-phase synthesis of GPR54-agonistic pentapeptide derivatives containing alkene- and fluoroalkene-dipeptide isosteresA novel one-pot reaction involving organocopper-mediated reduction/transmetalation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteresStereoselective Synthesis of 3,6-Disubstituted-3,6-dihydropyridin-2-ones as Potential Diketopiperazine Mimetics Using Organocopper-Mediatedanti-SN2‘ Reactions and Their Use in the Preparation of Low-Molecule CXCR4 AntagonistsSynthesis of (Z)-Alkene and (E)-Fluoroalkene-Containing Diketopiperazine Mimetics Utilizing Organocopper-Mediated Reduction−Alkylation and Diastereoselectivity Examination Using DFT CalculationsUnequivocal Synthesis of (Z)-Alkene and (E)-Fluoroalkene Dipeptide Isosteres To Probe Structural Requirements of the Peptide Transporter PEPT1Diastereoselective Synthesis of ψ[(E)-CHCMe]- and ψ[(Z)-CHCMe]-Type Dipeptide Isosteres by Organocopper-Mediatedanti-SN2‘ ReactionDiastereoselective Synthesis ofψ[(E)-CMeCH]- andψ[(E)-CMeCMe]- Type Dipeptide Isosteres Based on Organocopper-Mediatedanti-SN2‘ ReactionStereoselective synthesis of (Z)-alkene-containing proline dipeptide mimetics
P50
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P50
description
researcher ORCID ID = 0000-0002-6092-2678
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wetenschapper
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name
Ayumu Niida
@ast
Ayumu Niida
@en
Ayumu Niida
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Ayumu Niida
@nl
type
label
Ayumu Niida
@ast
Ayumu Niida
@en
Ayumu Niida
@es
Ayumu Niida
@nl
prefLabel
Ayumu Niida
@ast
Ayumu Niida
@en
Ayumu Niida
@es
Ayumu Niida
@nl
P106
P31
P496
0000-0002-6092-2678