about
NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple MyelomaIn situ study of chemokine and chemokine-receptor expression in Kaposi sarcoma.Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer.The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myelomaToward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitorsAxitinib induces DNA damage response leading to senescence, mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cellsGenotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells.Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1.Inhibition of glycogen synthase kinase-3 increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of STAT3.Chemotherapy-elicited upregulation of NKG2D and DNAM-1 ligands as a therapeutic target in multiple myeloma.A role for PKCtheta in outside-in alpha(IIb)beta3 signaling.Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.Recruitment of circulating NK cells through decidual tissues: a possible mechanism controlling NK cell accumulation in the uterus during early pregnancy.IL-15 inhibits IL-7Rα expression by memory-phenotype CD8⁺ T cells in the bone marrow.Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis.The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in Multiple Myeloma: modulation by Bromodomain and Extra-Terminal (BET) protein inhibitorsCancer Exosomes as Conveyors of Stress-Induced Molecules: New Players in the Modulation of NK Cell ResponseBone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription FactorHitting More Birds with a Stone: Impact of TGF-β on ILC Activity in Cancer
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description
researcher ORCID ID = 0000-0001-5461-9026
@en
wetenschapper
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name
Alessandra Soriani
@ast
Alessandra Soriani
@en
Alessandra Soriani
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Alessandra Soriani
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type
label
Alessandra Soriani
@ast
Alessandra Soriani
@en
Alessandra Soriani
@es
Alessandra Soriani
@nl
altLabel
Alessandra SORIANI
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prefLabel
Alessandra Soriani
@ast
Alessandra Soriani
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Alessandra Soriani
@es
Alessandra Soriani
@nl
P106
P1153
36148757300
P21
P31
P496
0000-0001-5461-9026