about
Oxysterols in the pathogenesis of major chronic diseasesOxidized cholesterol as the driving force behind the development of Alzheimer's diseaseLoading into nanoparticles improves quercetin's efficacy in preventing neuroinflammation induced by oxysterolsWine consumption and intestinal redox homeostasisInhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol.Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review).Signaling kinases modulated by 4-hydroxynonenal.4-Hydroxynonenal and cholesterol oxidation products in atherosclerosis.Activation of the mitochondrial pathway of apoptosis by oxysterols.Detection of cytochrome P4503A (CYP3A) in human hepatic stellate cells.4-hydroxynonenal: a membrane lipid oxidation product of medicinal interest.4-Hydroxynonenal-protein adducts: A reliable biomarker of lipid oxidation in liver diseases.Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets.Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammationCholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry.Cholesterol oxidation products in the vascular remodeling due to atherosclerosis.Dietary lipids and their oxidized products in Alzheimer's disease.Inflammation-related gene expression by lipid oxidation-derived products in the progression of atherosclerosis.The link between altered cholesterol metabolism and Alzheimer's disease.Metalloproteinases and metalloproteinase inhibitors in age-related diseases.The role of oxysterols in vascular ageing.Oxysterols and mechanisms of survival signaling.Nrf2 antioxidant defense is involved in survival signaling elicited by 27-hydroxycholesterol in human promonocytic cells.Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability.Survival signaling elicited by 27-hydroxycholesterol through the combined modulation of cellular redox state and ERK/Akt phosphorylation.Evidence of cell damage induced by major components of a diet-compatible mixture of oxysterols in human colon cancer CaCo-2 cell line.Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime.The core-aldehyde 9-oxononanoyl cholesterol increases the level of transforming growth factor beta1-specific receptors on promonocytic U937 cell membranes.Early involvement of ROS overproduction in apoptosis induced by 7-ketocholesterol.Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells.Physiological amounts of ascorbate potentiate phorbol ester-induced nuclear-binding of AP-1 transcription factor in cells of macrophagic lineage.Modulation of hepatic fibrogenesis by antioxidants.Nuclear factor kB is activated by arachidonic acid but not by eicosapentaenoic acid.Molecular signaling involved in oxysterol-induced β₁-integrin over-expression in human macrophages.Role of aldehyde metabolizing enzymes in mediating effects of aldehyde products of lipid peroxidation in liver cells.Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocatechin-3-gallate.Molecular signaling operated by a diet-compatible mixture of oxysterols in up-regulating CD36 receptor in CD68 positive cells.Alternate-day fasting protects the rat heart against age-induced inflammation and fibrosis by inhibiting oxidative damage and NF-kB activation.Oxidation as a crucial reaction for cholesterol to induce tissue degeneration: CD36 overexpression in human promonocytic cells treated with a biologically relevant oxysterol mixture.The role of p38 MAPK in the induction of intestinal inflammation by dietary oxysterols: modulation by wine phenolics.
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0002-3422-821X
@en
name
Gabriella Leonarduzzi
@ast
Gabriella Leonarduzzi
@en
Gabriella Leonarduzzi
@es
Gabriella Leonarduzzi
@nl
type
label
Gabriella Leonarduzzi
@ast
Gabriella Leonarduzzi
@en
Gabriella Leonarduzzi
@es
Gabriella Leonarduzzi
@nl
prefLabel
Gabriella Leonarduzzi
@ast
Gabriella Leonarduzzi
@en
Gabriella Leonarduzzi
@es
Gabriella Leonarduzzi
@nl
P106
P1153
6603736269
P21
P31
P496
0000-0002-3422-821X