In vivo CRISPR editing with no detectable genome-wide off-target mutations

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In vivo CRISPR editing with no detectable genome-wide off-target mutations

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article publié dans la revue scientifique Nature

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scientific article published in Nature

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wetenschappelijk artikel

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наукова стаття, опублікована в Nature у вересні 2018

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In vivo CRISPR editing with no detectable genome-wide off-target mutations

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In vivo CRISPR editing with no detectable genome-wide off-target mutations

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In vivo CRISPR editing with no detectable genome-wide off-target mutations

@en

In vivo CRISPR editing with no detectable genome-wide off-target mutations

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In vivo CRISPR editing with no detectable genome-wide off-target mutations

@en

In vivo CRISPR editing with no detectable genome-wide off-target mutations

@nl

P1476

In vivo CRISPR editing with no detectable genome-wide off-target mutations

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P2093

Alba Carreras

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Frank Seeliger

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J Keith Joung

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Jimmy A Guo

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Jose Malagon-Lopez

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Kendell Clement

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Lorenz M Mayr

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Luca Pinello

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Maggie L Bobbin

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Marcello Maresca

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P2860

The Sequence Alignment/Map format and SAMtools

DNA targeting specificity of RNA-guided Cas9 nucleases

Open-source guideseq software for analysis of GUIDE-seq data.

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing

Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture.

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.

WGE: a CRISPR database for genome engineering.

Defining and improving the genome-wide specificities of CRISPR-Cas9 nucleases.

P2888

s41586-018-0500-9

P304

416-419

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scholarly article

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10.1038/S41586-018-0500-9

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P407

English

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7723

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561

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Sara P Garcia

Roberto Nitsch

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2018-09-12T00:00:00Z

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P6179

1106931806

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P698

30209390

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P921

CRISPR

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6194229

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