Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
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RhoA: a therapeutic target for chronic myeloid leukemiaDepletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoformsAssociation of HLA Class I and Class II genes with bcr-abl transcripts in leukemia patients with t(9;22) (q34;q11)Approaches of targeting Rho GTPases in cancer drug discoveryModeling of Chronic Myeloid Leukemia: An Overview of In Vivo Murine and Human Xenograft ModelsTransformation of myeloid leukemia cells to cytokine independence by Bcr-Abl is suppressed by kinase-defective HckMultiple signaling interactions of Abl and Arg kinases with the EphB2 receptorRegulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptorPhosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signalingIdentification of cancer genes by mutational profiling of tumor genomesNovel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia CellsEmergence of FGFR family gene fusions as therapeutic targets in a wide spectrum of solid tumoursActivation of the Abl tyrosine kinase in vivo by Src homology 3 domains from the Src homology 2/Src homology 3 adaptor Nck.Interactions of p62(dok) with p210(bcr-abl) and Bcr-Abl-associated proteins.Measurable residual disease testing in acute myeloid leukaemia.Chimeric RNAs in cancer and normal physiology.Underdetermination in evidence-based medicine.Light microscopic detection of BCR-ABL transcripts after in-cell RT-PCR: fusion gene expression might correlate with clinical evolution of chronic myeloid leukemia.Targeting neighbouring poly(purine.pyrimidine) sequences located in the human bcr promoter by triplex-forming oligonucleotides.BCR/ABL transcripts and leukemia phenotype: an unsolved puzzle.High-dose imatinib for newly diagnosed chronic phase chronic myeloid leukemia patients--systematic review and meta-analysis.[Bone marrow histology from the clinical point of view].Significance of BCR-ABL transcripts in bone marrow aspirates of Philadelphia-negative essential thrombocythemia patients.In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications.Pathological interactions between hematopoietic stem cells and their niche revealed by mouse models of primary myelofibrosis.Patan hospital experience in treating philadelphia chromosome/BCR-ABL1 positive chronic myeloid leukemia patients with gleevec (imatinib mesylate); the first generation specific tyrosine kinase inhibitor.Cytogenetics and molecular genetics of childhood leukemia.Interplay between kinase domain autophosphorylation and F-actin binding domain in regulating imatinib sensitivity and nuclear import of BCR-ABL.Stem cell factor and chronic myeloid leukemia CD34+ cells.Towards a molecular understanding of polycythemia rubra vera.Expression of a Src family kinase in chronic myelogenous leukemia cells induces resistance to imatinib in a kinase-dependent manner.Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell linesRegulation of the interferon regulatory factor-8 (IRF-8) tumor suppressor gene by the signal transducer and activator of transcription 5 (STAT5) transcription factor in chronic myeloid leukemiaMetabolism considerations for kinase inhibitors in cancer treatmentRecent advances in the molecular and cellular biology of chronic myeloid leukaemia: lessons to be learned from the laboratory.Preparation and application of antibodies to phosphoamino acid sequences.Extensive gene-specific translational reprogramming in a model of B cell differentiation and Abl-dependent transformationChronic myelogenous leukaemia--new therapeutic principles.Current status of ribozymes as gene therapy agents for cancer.Alternative splicing regulated by butyrate in bovine epithelial cells.
P2860
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P2860
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
description
article publié dans la revue scientifique Nature
@fr
scientific article published in Nature
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в Nature в червні 1985
@uk
name
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
@en
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
@nl
type
label
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
@en
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
@nl
prefLabel
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
@en
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
@nl
P2093
P356
P1433
P1476
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
@en
P2093
B Lifshitz
E Shtivelman
P2888
P304
P356
10.1038/315550A0
P407
P577
1985-06-01T00:00:00Z
P6179
1045340731