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Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factorsIntranuclear Trafficking: Organization and Assembly of Regulatory Machinery for Combinatorial Biological ControlMitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cellsRegulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activityCbfbeta interacts with Runx2 and has a critical role in bone developmentSWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiationThe Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasionDefinitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.Insight into regulatory factor targeting to transcriptionally active subnuclear sites.Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.Intranuclear trafficking of transcription factors: implications for biological control.Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization.Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.Contributions of nuclear architecture and chromatin to vitamin D-dependent transcriptional control of the rat osteocalcin gene.Subnuclear organization and trafficking of regulatory proteins: implications for biological control and cancer.Effect of sodium hypochlorite on human pulp cells: an in vitro study.Runx2 activity in committed osteoblasts is not essential for embryonic skeletogenesis.Specificity protein 7 is not essential for tooth morphogenesis.Sp7 and Runx2 molecular complex synergistically regulate expression of target genes.Loss of Runx2 in committed osteoblasts impairs postnatal skeletogenesis.Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.Chondrocyte-specific regulatory activity of Runx2 is essential for survival and skeletal developmentRunx2 regulates the gene network associated with insulin signaling and energy homeostasisFunctional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair.Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.Myeloma cell-derived Runx2 promotes myeloma progression in bone.Transcriptional Auto-Regulation of RUNX1 P1 Promoter.Runx2 regulates endochondral ossification through control of chondrocyte proliferation and differentiation.MicroRNA 665 Regulates Dentinogenesis through MicroRNA-Mediated Silencing and Epigenetic MechanismsNetworks and hubs for the transcriptional control of osteoblastogenesis.Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling.Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone.Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancerNuclear microenvironments in biological control and cancer.Smooth muscle cell-specific runx2 deficiency inhibits vascular calcification.Biphasic peptide amphiphile nanomatrix embedded with hydroxyapatite nanoparticles for stimulated osteoinductive response.Heparanase promotes myeloma progression by inducing mesenchymal features and motility of myeloma cellsGenetic and epigenetic regulation in nuclear microenvironments for biological control in cancerSubnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic developmentHeparanase inhibits osteoblastogenesis and shifts bone marrow progenitor cell fate in myeloma bone disease.
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P50
description
researcher ORCID ID = 0000-0002-0847-8266
@en
wetenschapper
@nl
name
Amjad Javed
@ast
Amjad Javed
@en
Amjad Javed
@es
Amjad Javed
@nl
type
label
Amjad Javed
@ast
Amjad Javed
@en
Amjad Javed
@es
Amjad Javed
@nl
prefLabel
Amjad Javed
@ast
Amjad Javed
@en
Amjad Javed
@es
Amjad Javed
@nl
P1153
35418176300
P31
P496
0000-0002-0847-8266