Heparanase inhibits osteoblastogenesis and shifts bone marrow progenitor cell fate in myeloma bone disease. - Wikidata - wikimedia - TriplyDB

Heparanase inhibits osteoblastogenesis and shifts bone marrow progenitor cell fate in myeloma bone disease.

Heparanase inhibits osteoblastogenesis and shifts bone marrow progenitor cell fate in myeloma bone disease.

http://www.wikidata.org/entity/Q37204761

about

Treatment of multiple myeloma bone disease: experimental and clinical data.Myeloma cell-derived Runx2 promotes myeloma progression in bone.FGF23 is elevated in multiple myeloma and increases heparanase expression by tumor cells.Dissecting the multiple myeloma-bone microenvironment reveals new therapeutic opportunities Heparanase promotes myeloma progression by inducing mesenchymal features and motility of myeloma cells The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics.Adipocyte-derived players in hematologic tumors: useful novel targets?Heparanase overexpression down-regulates syndecan-1 expression in a gallbladder carcinoma cell line.Adipocyte-Lineage Cells Support Growth and Dissemination of Multiple Myeloma in Bone.Bone marrow micro-environment is a crucial player for myelomagenesis and disease progression.Surgical thyroparathyroidectomy prevents progression of 5TGM1 murine multiple myeloma in vivo.Polymorphisms in the heparanase gene in multiple myeloma association with bone morbidity and survival

P2860

Q30868833-6FC08E64-145C-46C6-BE62-516234B67ED4 Q35692401-DFBC3520-3670-4C89-A7CD-6A1FAB34C206 Q36260612-8AF7B58E-E3EE-45E1-9BB2-9AF071FC3C58 Q36447553-140CECF8-ABD6-49DA-A9EA-830A1CBE0801 Q36998235-098D8853-1D49-4CC4-B973-AEE0E7801B57 Q38238094-0A2F5632-2006-4009-A4E3-14FE1773A690 Q38259527-6AAED68F-7664-47DE-A559-FE8D1E55D73F Q38709903-5512CFFE-5E4A-4FB9-9561-5D328A949296 Q38736038-DAF53047-853A-452C-826B-E22A69F695D1 Q39093915-74921F53-E8B8-4D36-A2D4-BB348B98B78C Q55265829-2DE759A7-6BDB-40E1-AD08-392E5ED53CD0 Q59245028-E7E4AFA1-506C-4713-B9F0-155D08F92C7A

P2860

Heparanase inhibits osteoblastogenesis and shifts bone marrow progenitor cell fate in myeloma bone disease.

http://www.wikidata.org/entity/Q37204761

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 27 July 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Heparanase inhibits osteoblast ...... fate in myeloma bone disease.

@en

Heparanase inhibits osteoblast ...... fate in myeloma bone disease.

@nl

type

label

Heparanase inhibits osteoblast ...... fate in myeloma bone disease.

@en

Heparanase inhibits osteoblast ...... fate in myeloma bone disease.

@nl

prefLabel

Heparanase inhibits osteoblast ...... fate in myeloma bone disease.

@en

Heparanase inhibits osteoblast ...... fate in myeloma bone disease.

@nl

P1433

Q37204761-96509EFA-FA21-4066-BE24-F1E8708CB2A1

P1476

Q37204761-A176CA3E-4EFF-4280-A32C-6D9A6C0A1504

P2093

Q37204761-11A5CDC3-EC6F-4D40-9D0E-1AB699403016

Q37204761-27390617-5FDD-49FD-B53E-519BD2E2581C

Q37204761-6D32A1B2-87A7-402E-9B5D-C4040C4D439E

Q37204761-803CD591-D45D-4C06-A69E-BC13893AE530

Q37204761-B39E2F97-8673-4798-A888-16CA65C06894

Q37204761-C4DC6E3D-E158-4839-97AD-6CB1B384C069

P2860

Q37204761-050DE85C-BCE9-45F7-8E17-27A578AE1C3A

Q37204761-1C92BB70-4F8F-4240-841F-698E6B2B58C3

Q37204761-1F034A5A-7888-4363-924B-C2580D767617

Q37204761-29CB563D-5BAD-4783-BE8D-BE3901ED0FD1

Q37204761-4994C248-99B5-4311-BC39-0848AFF1D555

Q37204761-4F3D2121-E801-4C0B-B655-63744EE85D47

Q37204761-508567F9-0C8E-4087-BC51-E43C9A3E4F7C

Q37204761-5DCD237B-7667-4578-A55A-FA18B2FA80D5

Q37204761-627575CA-B5F8-4450-9660-8668DA5A1149

Q37204761-64D1DE6C-B1EE-4F4A-AA2B-9724FF9B01B6

P304

Q37204761-CDE05A82-1B21-400D-BE50-68722002FC0B

P31

Q37204761-C373FCDC-9475-4656-AEA6-1302D08B3306

P356

Q37204761-E8C09833-4851-47D6-AFA7-B60768991E52

P433

Q37204761-37FA5D54-9D41-4984-A4A8-734CF3834B8E

P478

Q37204761-865806FA-6B59-4C5B-BE15-3D77A409B212

P50

Q37204761-78B6FF37-EAB1-4A05-8864-495536FC9853

Q37204761-FDC17297-949D-4DB7-8D19-5DB37E6DF24D

P577

Q37204761-283B796F-E16D-4656-AAFF-0E49B366381C

P5875

Q37204761-FE64346A-311E-436B-80E2-6309953CBEAB

P698

Q37204761-0F082399-415C-454C-A626-4EBD617DA743

P921

Q37204761-F5BB98D3-6680-4CC9-832F-AC29B90C1FFE

P932

Q37204761-2ECCF9DC-78A4-47E0-B5FE-F54D570E2E1E

P356

J.BONE.2013.07.024

P1433

P1476

Heparanase inhibits osteoblast ...... l fate in myeloma bone disease

@en

P2093

Jian Ruan

http://www.w3.org/2001/XMLSchema#string

Li Nan

http://www.w3.org/2001/XMLSchema#string

Ralph D Sanderson

http://www.w3.org/2001/XMLSchema#string

Rongcheng Luo

http://www.w3.org/2001/XMLSchema#string

Timothy N Trotter

http://www.w3.org/2001/XMLSchema#string

Yang Yang

http://www.w3.org/2001/XMLSchema#string

P2860

Wnt/β-catenin signaling and disease

Identification of active-site residues of the pro-metastatic endoglycosidase heparanase

Soluble syndecan-1 promotes growth of myeloma tumors in vivo

Heparanase: structure, biological functions, and inhibition by heparin-derived mimetics of heparan sulfate

Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis.

Bone metastasis: mechanisms and therapeutic opportunities.

Heparanase enhances local and systemic osteolysis in multiple myeloma by upregulating the expression and secretion of RANKL

Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis.

New insight in the mechanism of osteoclast activation and formation in multiple myeloma: focus on the receptor activator of NF-kappaB ligand (RANKL).

The WNT inhibitor Dickkopf 1 and bone morphogenetic protein 4 rescue adipogenesis in hypertrophic obesity in humans.

P304

10-17

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.BONE.2013.07.024

http://www.w3.org/2001/XMLSchema#string

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

57

http://www.w3.org/2001/XMLSchema#string

P50

P577

2013-07-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

253338119

http://www.w3.org/2001/XMLSchema#string

P698

23895995

http://www.w3.org/2001/XMLSchema#string

P921

P932

3786009

http://www.w3.org/2001/XMLSchema#string