Heparanase inhibits osteoblastogenesis and shifts bone marrow progenitor cell fate in myeloma bone disease.
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Treatment of multiple myeloma bone disease: experimental and clinical data.Myeloma cell-derived Runx2 promotes myeloma progression in bone.FGF23 is elevated in multiple myeloma and increases heparanase expression by tumor cells.Dissecting the multiple myeloma-bone microenvironment reveals new therapeutic opportunitiesHeparanase promotes myeloma progression by inducing mesenchymal features and motility of myeloma cellsThe Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics.Adipocyte-derived players in hematologic tumors: useful novel targets?Heparanase overexpression down-regulates syndecan-1 expression in a gallbladder carcinoma cell line.Adipocyte-Lineage Cells Support Growth and Dissemination of Multiple Myeloma in Bone.Bone marrow micro-environment is a crucial player for myelomagenesis and disease progression.Surgical thyroparathyroidectomy prevents progression of 5TGM1 murine multiple myeloma in vivo.Polymorphisms in the heparanase gene in multiple myeloma association with bone morbidity and survival
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Heparanase inhibits osteoblastogenesis and shifts bone marrow progenitor cell fate in myeloma bone disease.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Heparanase inhibits osteoblast ...... fate in myeloma bone disease.
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Heparanase inhibits osteoblast ...... fate in myeloma bone disease.
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type
label
Heparanase inhibits osteoblast ...... fate in myeloma bone disease.
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Heparanase inhibits osteoblast ...... fate in myeloma bone disease.
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Heparanase inhibits osteoblast ...... fate in myeloma bone disease.
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Heparanase inhibits osteoblast ...... fate in myeloma bone disease.
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P2093
P2860
P1433
P1476
Heparanase inhibits osteoblast ...... l fate in myeloma bone disease
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P2093
Ralph D Sanderson
Rongcheng Luo
Timothy N Trotter
P2860
P356
10.1016/J.BONE.2013.07.024
P577
2013-07-27T00:00:00Z