about
Role of LXRs in control of lipogenesisA direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RARLXR, a nuclear receptor that defines a distinct retinoid response pathwayGenetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylaseRegulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbetaFGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesisEndocrine fibroblast growth factors 15/19 and 21: from feast to famineMicroRNA let-7 regulates 3T3-L1 adipogenesisCloning and expression of full-length cDNA encoding human vitamin D receptorFGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation responseFibroblast growth factor 21: from pharmacology to physiologyActivation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissueNuclear Receptors, RXR, and the Big BangThe Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathwayStructural Conservation of Ligand Binding Reveals a Bile Acid-like Signaling Pathway in NematodesStructural insights into gene repression by the orphan nuclear receptor SHPThe nuclear receptor superfamily: the second decadeChromosomal localization of the human retinoid X receptorsHuman white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterolsRegulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and betaAnatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional networkInternational Union of Pharmacology. LXII. The NR1H and NR1I receptors: constitutive androstane receptor, pregnene X receptor, farnesoid X receptor alpha, farnesoid X receptor beta, liver X receptor alpha, liver X receptor beta, and vitamin D receptLXRS and FXR: the yin and yang of cholesterol and fat metabolismExpression of ABCG5 and ABCG8 is required for regulation of biliary cholesterol secretionActivation of mammalian retinoid X receptors by the insect growth regulator methopreneOverexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretionOxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcriptionActivation of the orphan nuclear receptor steroidogenic factor 1 by oxysterolsDifferential expression and activation of a family of murine peroxisome proliferator-activated receptorsPPARγ in vagal neurons regulates high-fat diet induced thermogenesisDe-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilaseRegulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxification processesThe RXR heterodimers and orphan receptorsEndocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21Nuclear receptor LRH-1 induces the reproductive neuropeptide kisspeptin in the hypothalamus.Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in miceLiver X receptor alpha is a transcriptional repressor of the uncoupling protein 1 gene and the brown fat phenotype.Commentary: the year in nuclear receptor control of metabolismNuclear receptor regulation of cholesterol and bile acid metabolism.Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver.
P50
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P50
description
researcher ORCID ID = 0000-0002-4355-0796
@en
wetenschapper
@nl
name
David J Mangelsdorf
@ast
David J Mangelsdorf
@en
David J Mangelsdorf
@nl
type
label
David J Mangelsdorf
@ast
David J Mangelsdorf
@en
David J Mangelsdorf
@nl
prefLabel
David J Mangelsdorf
@ast
David J Mangelsdorf
@en
David J Mangelsdorf
@nl
P1006
P214
P1006
P106
P1580
P21
P214
P31
P496
0000-0002-4355-0796
P5361
MangelsdorfDavidJ(DavidJohn)1958-
P569
1958-01-01T00:00:00Z
P7859
lccn-no2003124839