about
MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.Discovery, molecular and pharmacological characterization of GSA-10, a novel small-molecule positive modulator of Smoothened.Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathway.Design, synthesis and biological characterization of a new class of osteogenic (1H)-quinolone derivatives.[Structure of the Smoothened receptor].Pathological modelling of pigmentation disorders associated with Hutchinson-Gilford Progeria Syndrome (HGPS) revealed an impaired melanogenesis pathway in iPS-derived melanocytes.
P50
description
researcher ORCID ID = 0000-0002-7264-9031
@en
name
Lucile Hoch
@ast
Lucile Hoch
@en
Lucile Hoch
@es
Lucile Hoch
@nl
type
label
Lucile Hoch
@ast
Lucile Hoch
@en
Lucile Hoch
@es
Lucile Hoch
@nl
prefLabel
Lucile Hoch
@ast
Lucile Hoch
@en
Lucile Hoch
@es
Lucile Hoch
@nl
P21
P31
P496
0000-0002-7264-9031