MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.

MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.

Item
http://www.wikidata.org/entity/Q35552174
Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI InhibitorsSynthetic Small Molecule Inhibitors of Hh Signaling As Anti-Cancer Chemotherapeutics.Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype.I only have eye for ewe: the discovery of cyclopamine and development of Hedgehog pathway-targeting drugsHedgehog Controls Quiescence and Activation of Neural Stem Cells in the Adult Ventricular-Subventricular Zone.Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathway.Strategies to target the Hedgehog signaling pathway for cancer therapy.Novel smoothened antagonists as anti-neoplastic agents for the treatment of osteosarcoma.Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe.Smoothened-antagonists reverse homogentisic acid-induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria.Best Matching Protein Conformations and Docking Programs for a Virtual Screening Campaign Against SMO Receptor.
P2860

MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.

Item
http://www.wikidata.org/entity/Q35552174
description
2015 nî lūn-bûn
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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2015 թվականի հունվարին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
@zh-mo
2015年論文
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2015年论文
@wuu
name
MRT-92 inhibits Hedgehog signa ...... in of the Smoothened receptor.
@ast
MRT-92 inhibits Hedgehog signa ...... in of the Smoothened receptor.
@en
type
label
MRT-92 inhibits Hedgehog signa ...... in of the Smoothened receptor.
@ast
MRT-92 inhibits Hedgehog signa ...... in of the Smoothened receptor.
@en
prefLabel
MRT-92 inhibits Hedgehog signa ...... in of the Smoothened receptor.
@ast
MRT-92 inhibits Hedgehog signa ...... in of the Smoothened receptor.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
MRT-92 inhibits Hedgehog signa ...... ain of the Smoothened receptor
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932