about
Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subsetFunctional regulation of monocyte-derived dendritic cells by microRNAsCognate antigen engagement on parenchymal cells stimulates CD8+ T cell proliferation in situ.Cytokine response of T-cell subsets from Brucella abortus-infected mice to soluble Brucella proteins.Endogenous gamma interferon mediates resistance to Brucella abortus infectionNegative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling.Rotavirus infection induces transient pancreatic involution and hyperglycemia in weanling mice.Glucocorticoid receptor deficient thymic and peripheral T cells develop normally in adult mice.Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation.NKT cell stimulation with glycolipid antigen in vivo: costimulation-dependent expansion, Bim-dependent contraction, and hyporesponsiveness to further antigenic challenge.TCR-mediated activation promotes GITR upregulation in T cells and resistance to glucocorticoid-induced death.The closely related CD103+ dendritic cells (DCs) and lymphoid-resident CD8+ DCs differ in their inflammatory functionsDefects in the Bcl-2-regulated apoptotic pathway lead to preferential increase of CD25 low Foxp3+ anergic CD4+ T cells.Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cellsDifferential induction of macrophage-derived cytokines by live and dead intracellular bacteria in vitroEndogenous interleukin-12 is involved in resistance to Brucella abortus infection.Tumor necrosis factor alpha and interleukin-12 contribute to resistance to the intracellular bacterium Brucella abortus by different mechanismsEither B7-1 or B7-2 is required for Listeria monocytogenes-specific production of gamma interferon and interleukin-2.The Rel subunit of NF-kappaB-like transcription factors is a positive and negative regulator of macrophage gene expression: distinct roles for Rel in different macrophage populationsInnate immune surveillance of spontaneous B cell lymphomas by natural killer cells and gammadelta T cells.Plasmacytoid dendritic cells are short-lived: reappraising the influence of migration, genetic factors and activation on estimation of lifespan.Selected Toll-like receptor ligands and viruses promote helper-independent cytotoxic T cell priming by upregulating CD40L on dendritic cells.The regulation of the development and function of dendritic cell subsets by GM-CSF: more than a hematopoietic growth factor.The role of microRNAs in lymphopoiesis.XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.Heterogeneity, functional specialization and differentiation of monocyte-derived dendritic cells.Rapid deletion and inactivation of CTLs upon recognition of a number of target cells over a critical threshold.Functional cytotoxic T lymphocytes against IGRP206-214 predict diabetes in the non-obese diabetic mouse.Loss of c-Cbl RING finger function results in high-intensity TCR signaling and thymic deletion.Local effector failure in mesothelioma is not mediated by CD4+ CD25+ T-regulator cells.Deliberately provoking local inflammation drives tumors to become their own protective vaccine site.NK cells promote peritoneal xenograft rejection through an IFN-gamma-dependent mechanism.Drosha controls dendritic cell development by cleaving messenger RNAs encoding inhibitors of myelopoiesis.Monocyte-Derived Dendritic Cells Promote Th Polarization, whereas Conventional Dendritic Cells Promote Th Proliferation.Inflammation conditions mature dendritic cells to retain the capacity to present new antigens but with altered cytokine secretion function.Resident and monocyte-derived dendritic cells become dominant IL-12 producers under different conditions and signaling pathways.Characterization of an immediate splenic precursor of CD8+ dendritic cells capable of inducing antiviral T cell responses.Anti-CD45RB antibody deters xenograft rejection by modulating T cell priming and homing.Unlike CD4+ T-cell help, CD28 costimulation is necessary for effective primary CD8+ T-cell influenza-specific immunity.Functional deficiencies of peritoneal cells from gene-targeted mice lacking G-CSF or GM-CSF.
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0001-6974-0486
@en
name
Yifan Zhan
@ast
Yifan Zhan
@en
Yifan Zhan
@es
Yifan Zhan
@nl
type
label
Yifan Zhan
@ast
Yifan Zhan
@en
Yifan Zhan
@es
Yifan Zhan
@nl
prefLabel
Yifan Zhan
@ast
Yifan Zhan
@en
Yifan Zhan
@es
Yifan Zhan
@nl
P106
P1153
57205474859
P31
P496
0000-0001-6974-0486