about
Strategy for "detoxification" of a cancer-derived histone mutant based on mapping its interaction with the methyltransferase PRC2S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas.Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.
P50
description
Forscher
@de
chercheur
@fr
investigador
@es
researcher
@en
ricercatore
@it
研究者
@zh
name
Siddhant U Jain
@ast
Siddhant U Jain
@en
Siddhant U Jain
@es
Siddhant U Jain
@nl
type
label
Siddhant U Jain
@ast
Siddhant U Jain
@en
Siddhant U Jain
@es
Siddhant U Jain
@nl
prefLabel
Siddhant U Jain
@ast
Siddhant U Jain
@en
Siddhant U Jain
@es
Siddhant U Jain
@nl
P31
P496
0000-0002-7390-6757