about
sameAs
SMAD2 ser-465 ser-467 phosphorylatedL-serine 464 replaced with unknownL-alanine residue 354 replaced with L-threonineL-aspartic acid residue 300 replaced with L-alanineL-aspartic acid residue 300 replaced with L-asparagineL-proline residue 305 replaced with L-leucineL-alanine residue 354 replaced with L-threonine ser-465 ser-467 phosphorylatedL-aspartic acid residue 300 replaced with L-alanine ser-465 ser-467 phosphorylatedL-aspartic acid residue 300 replaced with L-asparagine ser-465 ser-467 phosphorylatedL-proline residue 305 replaced with L-leucine ser-465 ser-467 phosphorylatedSMAD2 ser-465 ser-467 ser-220 phosphorylatedSMAD2 ser-unknown phosphorylatedSMAD2 ser-465 ser-467 phosphorylated [nucleoplasm]
P279
P688
Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteinsNodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cellsThe left-right axis is regulated by the interplay of Coco, Xnr1 and derrière in Xenopus embryosCholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesisEpithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusionDifferential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formationZNF580, a novel C2H2 zinc-finger transcription factor, interacts with the TGF-β signal molecule Smad2MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signalingDual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexesSmad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcriptionPin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteinsHeteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4Cellular response to hypoxia involves signaling via Smad proteinsMADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinomaBone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cellsHolding their own: the noncanonical roles of Smad proteinsHMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transitionHEB and E2A function as SMAD/FOXH1 cofactorsVascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endotheliumCharacterization of human FAST-1, a TGF beta and activin signal transducerPPM1A functions as a Smad phosphatase to terminate TGFbeta signalingSyntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalizationDisorder in a target for the smad2 mad homology 2 domain and its implications for binding and specificitySMAD proteins control DROSHA-mediated microRNA maturationPin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease.Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling
P921
Q50369588-0F13891D-6495-4849-AD27-C6FAA72FCA1CQ50369827-042B9122-5D1F-4C15-AC84-3415D0A0AE96Q50369828-8015BE57-6F80-4BAA-840C-3448668808A5Q50369829-BEC1081F-1AD2-468B-A30E-85C782C91033Q50369830-41F78531-75D8-4885-BC7D-449F86C5F8F7Q50369831-F8DD2EB8-D5BE-4A15-A96A-F38C182B9CF2Q50369834-9C09A8ED-E229-4EF2-A5C7-750B5FC9BBBBQ50369835-23230A0F-6BC6-4575-BC37-1E7349E5306CQ50369837-14990F03-E211-4EDB-819E-35CD9527D22EQ50369838-7882D9F6-E14E-4A15-986E-F5A3B1A31984Q50371987-450F6A32-7CE7-4D81-BFE2-43A72F70DE51Q50373600-A8DF0566-36D1-40A1-97A0-30C77A030202Q50677163-726E8664-6C76-4EFC-B8FF-3704AC851E86
P279
Q50255075-9B66250B-70DF-43E7-9BD6-B4D91E37AACDQ50255077-C1F64FDB-2EA2-4FD0-AF38-2B2B29ACC817Q50255084-98CC2EE6-2371-4A39-8EF6-149AF50179CAQ50256081-78EF92DA-7340-4CBB-8A74-09F70F52F6CDQ50256086-DB757574-E53C-4D6A-8C92-107123C680DBQ50256091-C3D4D7E1-79DF-4686-BCA7-D89DF7495E6CQ50257925-B4BED7A7-F004-4F0A-B563-CD6D1F70540CQ50257956-937E0E50-0B52-4B08-8D9B-C3B833AC90B3Q50257959-FD5B9ED5-7D29-42A1-A7E3-989223065E61Q50268880-D42325C3-E4C0-4179-B419-BE9E8DA50926Q50272226-EF25B26A-B2FF-433F-A87F-B91FD7A94319Q50272228-8A364D7D-1BB3-42B5-A6FA-FA40AF0A4E71Q50298181-F68DBD11-151B-402E-85FA-808C7A42C035
P527
Q24290752-427E8DD8-D34F-4A83-AD76-5441F535E1BBQ24293592-AC3566D1-2388-48D1-8935-F4048B5E76FCQ24293713-85F3DF94-7801-4180-95EF-5D14E242C212Q24294300-73C25E8C-3299-4948-8615-7C9E250DBC47Q24294844-B30F37B7-32F1-4C68-BE85-8869F07F13CEQ24297637-9EB318F8-7867-4319-809B-6BC5012DB28AQ24302554-44B483D6-C059-42D2-A22D-D0D0A2042BDAQ24304071-7047CFB9-FB9D-4DC0-AFDB-0B9BEA6B9D2EQ24310282-7069519F-D25C-4B88-BA3C-ACD0AC1D29D7Q24310852-F75E0428-01D9-469C-9D87-0ECB38695D3DQ24311810-CA81DD6F-4E02-41E8-83C1-5527D511E48FQ24313316-1D092B2C-326D-4522-ADC9-053A7F084F11Q24314569-33976C5B-4A13-4070-8D26-6E28893EC6A0Q24314661-F217CA23-89D5-4A54-8889-D4FE600EA826Q24314797-3F5F8474-6906-4D79-8541-F818954E4924Q24315119-CAF826F4-439A-4B1A-A5D1-D1C0CAF21C61Q24315838-C54D8532-B598-4F51-8F1A-26B19C3E6402Q24316045-01F1599B-23CA-4A37-93C1-C91972448A18Q24318681-4F3BA04C-D4BD-4351-AEB7-07A1DC41D842Q24320356-15A9244E-7C63-4788-8C17-F66EC5E59712Q24322926-53083AF3-A78B-403D-AB1C-B98CF0A3FE15Q24323087-17A9A3BA-66BE-4AD8-8BE0-05A81330429CQ24338559-FCAFC879-0EF2-40E1-854A-F1279DED4BB6Q28118751-D37E4793-657C-480E-831C-0B05F05F79AAQ28910316-6A5B9208-33EC-4837-B79F-D15C4B0FAED5Q28941771-6D54DF8D-E23C-4336-BE16-1DADE8662047Q35194715-3B1558BD-BCE2-4C25-9169-59DC2FBC27C7Q90465976-6820F11E-A445-4A5E-AD81-CB2C55609218
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in SMAD family member 2
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
SMAD family member 2
@en
SMAD family member 2
@nl
SMAD2
@ru
type
label
SMAD family member 2
@en
SMAD family member 2
@nl
SMAD2
@ru
altLabel
JV18-1
@en
MAD homolog 2
@en
Mad-related protein 2
@en
SMAD 2
@en
SMAD, mothers against DPP homolog 2
@en
SMAD2
@en
Sma- and Mad-related protein 2
@en
hMAD-2
@en
hSMAD2
@en
mother against DPP homolog 2
@en
prefLabel
SMAD family member 2
@en
SMAD family member 2
@nl
SMAD2
@ru
P361
P527
P637
P638
P672
P680
P681
P682
P705
P352
P486
P637
P672
P352
P486
P637
NP_001003652
NP_001129409
XP_005258316
XP_006722514
XP_011524286
XP_011524287
XP_016881234
XP_016881235
XP_016881236
P638
P672
D12.644.360.024.334.500.200
D12.776.157.057.170.500.200
D12.776.476.024.428.500.200
D12.776.744.741.750
D12.776.930.806.500.200
P680
P681
P682
P702
P703
P705
ENSP00000262160
ENSP00000349282
ENSP00000384449
ENSP00000465355
ENSP00000465971
ENSP00000466193
ENSP00000466254
ENSP00000467075
ENSP00000468202
ENSP00000468732