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The contribution of pyruvate cycling to loss of [6-3H]glucose during conversion of glucose to glycogen in hepatocytes: effects of insulin, glucose and acinar origin of hepatocytesHepatic differentiation of murine embryonic stem cellsHepatocyte-ductal transdifferentiation is mediated by reciprocal repression of SOX9 and C/EBPα.In vitro culture of embryonic mouse intestinal epithelium: cell differentiation and introduction of reporter genes.Dexamethasone treatment induces the reprogramming of pancreatic acinar cells to hepatocytes and ductal cells.Transdifferentiation of pancreas to liver.Zscan4 is regulated by PI3-kinase and DNA-damaging agents and directly interacts with the transcriptional repressors LSD1 and CtBP2 in mouse embryonic stem cellsMicroRNA-122: a novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity.Phosphoinositide 3-kinase alpha-dependent regulation of branching morphogenesis in murine embryonic lung: evidence for a role in determining morphogenic properties of FGF7Bile ducts as a source of pancreatic beta cells.Therapeutic potential of transdifferentiated cells.The molecular basis of transdifferentiation.Epithelial metaplasia and the development of cancer.Transdifferentiation in developmental biology, disease, and in therapy.Islet-like cell clusters occur naturally in human gall bladder and are retained in diabetic conditions.New sources of beta-cells for treating diabetes.Transdifferentiation, metaplasia and tissue regeneration.How does inflammation cause Barrett's metaplasia?The role of Cdx2 in Barrett's metaplasia.Conversion of one cell type into another: implications for understanding organ development, pathogenesis of cancer and generating cells for therapy.Hollow fibre membrane bioreactors for tissue engineering applications.Highly Potent and Isoform Selective Dual Site Binding Tankyrase/Wnt Signaling Inhibitors That Increase Cellular Glucose Uptake and Have Antiproliferative Activity.In vitro reprogramming of pancreatic alpha cells towards a beta cell phenotype following ectopic HNF4α expression.The enone motif of (+)-grandifloracin is not essential for 'anti-austerity' antiproliferative activity.Hnf4α is a key gene that can generate columnar metaplasia in oesophageal epithelium.Transdifferentiation of pancreatic cells to hepatocytes.In vitro reprogramming of pancreatic cells to hepatocytes.Reprogramming of liver to pancreas.Betacellulin inhibits amylase and glucagon production and promotes beta cell differentiation in mouse embryonic pancreas.Expression of liver-enriched nuclear factors and their isoforms in alpha-fetoprotein-producing gastric carcinoma cells.Characterization of liver function in transdifferentiated hepatocytes.In vitro transdifferentiation of hepatoma cells into functional pancreatic cells.Induction and regulation of acute phase proteins in transdifferentiated hepatocytes.Xanthine oxidoreductase is asymmetrically localised on the outer surface of human endothelial and epithelial cells in culture.C/EBPalpha and C/EBPbeta are markers of early liver developmentKeratinocyte serum-free medium maintains long-term liver gene expression and function in cultured rat hepatocytes by preventing the loss of liver-enriched transcription factors.A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3.Isolation, culture, and characterisation of mouse embryonic oesophagus and intestine.Conversion of columnar to stratified squamous epithelium in the developing mouse oesophagus.Beta cells occur naturally in extrahepatic bile ducts of mice.
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description
researcher
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wetenschapper
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D Tosh
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D Tosh
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D Tosh
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type
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D Tosh
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D Tosh
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D Tosh
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D Tosh
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D Tosh
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D Tosh
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P106
P31
P496
0000-0002-4010-6649