about
The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cellsInhibition of human dyskerin as a new approach to target ribosome biogenesisInterleukin 6 downregulates p53 expression and activity by stimulating ribosome biogenesis: a new pathway connecting inflammation to cancerBeta-catenin/HuR post-transcriptional machinery governs cancer stem cell features in response to hypoxiaNucleolar function and size in cancer cellsThe p53 codon 72 proline allele is endowed with enhanced cell-death inducing potential in cancer cells exposed to hypoxia.Nucleolus, ribosomes, and cancerWhat the nucleolus says to a tumour pathologist.Dyskerin and cancer: more than telomerase. The defect in mRNA translation helps in explaining how a proliferative defect leads to cancer.The emerging role of RNA polymerase I transcription machinery in human malignancy: a clinical perspective.The importance of being (slightly) modified: The role of rRNA editing on gene expression control and its connections with cancer.Human ribosomes from cells with reduced dyskerin levels are intrinsically altered in translation.SnoRNA U50 levels are regulated by cell proliferation and rRNA transcription.Dyskerin depletion increases VEGF mRNA internal ribosome entry site-mediated translation.Selective inhibition of rRNA transcription downregulates E2F-1: a new p53-independent mechanism linking cell growth to cell proliferation.Loss of retinoblastoma tumor suppressor protein makes human breast cancer cells more sensitive to antimetabolite exposure.Different effects of ribosome biogenesis inhibition on cell proliferation in retinoblastoma protein- and p53-deficient and proficient human osteosarcoma cell lines.Dyskerin expression influences the level of ribosomal RNA pseudo-uridylation and telomerase RNA component in human breast cancer.Key role of the achievement of an appropriate ribosomal RNA complement for G1-S phase transition in H4-II-E-C3 rat hepatoma cells.Increased mortality rate and not impaired ribosomal biogenesis is responsible for proliferative defect in dyskeratosis congenita cell lines.Proportionally constant quantitative transmission of nucleolin and protein B23 in cycling cancer cellsThe basal-like breast carcinoma phenotype is regulated by SLUG gene expression.Thymidylate synthase protein expression and activity are related to the cell proliferation rate in human cancer cell lines.The p53-mediated sensitivity of cancer cells to chemotherapeutic agents is conditioned by the status of the retinoblastoma protein.Nucleolar size and activity are related to pRb and p53 status in human breast cancer.Healthy early preantral follicle can be obtained in a culture of frozen-thawed human ovarian tissue of 32 weeks.DKC1 gene mutations in human sporadic cancer.Relationship between dyskerin expression and telomerase activity in human breast cancer.JHDM1B expression regulates ribosome biogenesis and cancer cell growth in a p53 dependent manner.Turning Uridines around: Role of rRNA Pseudouridylation in Ribosome Biogenesis and Ribosomal Function.Dyskerin expression in human fetal, adult and neoplastic intrahepatic bile ducts: correlations with cholangiocarcinoma aggressiveness5'-Untranslated region of heat shock protein 70 mRNA drives translation under hypertonic conditionsRibosome biogenesis and control of cell proliferation: p53 is not aloneLocation of rRNA transcription to the nucleolar components: disappearance of the fibrillar centers in nucleoli of regenerating rat hepatocytesControversial relationship between the expression of the RB pathway components and RB protein phosphorylation in human breast cancerPrognostic relevance of a novel semiquantitative classification of Bcl2 immunohistochemical expression in human infiltrating ductal carcinomas of the breastRelationship between the RB1 mRNA level and the expression of phosphorylated RB protein in human breast cancers: their relevance in cell proliferation activity and patient clinical outcomeDesmoplastic small round-cell tumor: a case report on the large cell variant with immunohistochemical, ultrastructural, and molecular genetic analysisDetection of EWS chimeric transcripts by nested RT-PCR to allow reinfusion of uncontaminated peripheral blood stem cells in high-risk Ewing's tumor in childhoodThe Ribosome Biogenesis-Cancer Connection
P50
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P50
description
researcher
@en
wetenschapper
@nl
name
L L Montanaro
@en
L L Montanaro
@nl
type
label
L L Montanaro
@en
L L Montanaro
@nl
prefLabel
L L Montanaro
@en
L L Montanaro
@nl
P106
P31
P496
0000-0001-9776-9518