about
Adenoviral augmentation of elafin protects the lung against acute injury mediated by activated neutrophils and bacterial infectionC5a mediates peripheral blood neutrophil dysfunction in critically ill patientsLow-pathogenicity Mycoplasma spp. alter human monocyte and macrophage function and are highly prevalent among patients with ventilator-acquired pneumoniaCombined dysfunctions of immune cells predict nosocomial infection in critically ill patientsRecent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureusCathelicidin host defence peptide augments clearance of pulmonary Pseudomonas aeruginosa infection by its influence on neutrophil function in vivo.Diagnostic importance of pulmonary interleukin-1beta and interleukin-8 in ventilator-associated pneumoniaDifferential response to bacteria, and TOLLIP expression, in the human respiratory tract.Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia.A national survey of the diagnosis and management of suspected ventilator-associated pneumonia.Emergency pre-hospital management of patients admitted with acute asthmaMonocytes control second-phase neutrophil emigration in established lipopolysaccharide-induced murine lung injury.Validation of the DECAF score to predict hospital mortality in acute exacerbations of COPDEffectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial.Predictive value of cell-surface markers in infections in critically ill patients: protocol for an observational study (ImmuNe FailurE in Critical Therapy (INFECT) Study).Trappin-2 promotes early clearance of Pseudomonas aeruginosa through CD14-dependent macrophage activation and neutrophil recruitmentEarly PREdiction of Severe Sepsis (ExPRES-Sepsis) study: protocol for an observational derivation study to discover potential leucocyte cell surface biomarkersSecondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophagesIn vivo mononuclear cell tracking using superparamagnetic particles of iron oxide: feasibility and safety in humans.Aspirin reduces lipopolysaccharide-induced pulmonary inflammation in human models of ARDS.Serial characterisation of monocyte and neutrophil function after lung resection.Functional characterisation of human pulmonary monocyte-like cells in lipopolysaccharide-mediated acute lung inflammation.Diagnostic accuracy and cost analysis of the Alere™ i Influenza A&B near-patient test using throat swabs.The heterogeneity of systemic inflammation in bronchiectasis.The PEARL score predicts 90-day readmission or death after hospitalisation for acute exacerbation of COPD.A 29-year-old male with chest pain and haemoptysis.Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by β2-agonists, corticosteroids, and critical illness.The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system.Galectin-3 reduces the severity of pneumococcal pneumonia by augmenting neutrophil function.Erratum to: 'Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial'.Effect of granulocyte-macrophage colony-stimulating factor on neutrophil function in idiopathic bronchiectasis.Novel role for endogenous mitochondrial formylated peptide-driven formyl peptide receptor 1 signalling in acute respiratory distress syndrome.16S pan-bacterial PCR can accurately identify patients with ventilator-associated pneumonia.Early clinical experiences with nintedanib in three UK tertiary interstitial lung disease centres.Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation.Leukoreduced blood transfusion does not increase circulating soluble markers of inflammation: a randomized controlled trial.Excess Mucin Impairs Subglottic Epithelial Host Defense in Mechanically Ventilated Patients.A randomized controlled trial of peripheral blood mononuclear cell depletion in experimental human lung inflammation.Prognostic significance of the lung scintigraphy scan result and corresponding chest X-ray in patients with suspected pulmonary embolism.Oropharyngeal Microbiota in Frail Older Patients Unaffected by Time in Hospital.
P50
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P50
description
researcher
@en
wetenschapper
@nl
name
A J Simpson
@en
A J Simpson
@nl
type
label
A J Simpson
@en
A J Simpson
@nl
prefLabel
A J Simpson
@en
A J Simpson
@nl
P106
P31
P496
0000-0003-4731-7294