about
ELR510444 inhibits tumor growth and angiogenesis by abrogating HIF activity and disrupting microtubules in renal cell carcinomaAcquired cellular resistance to flavopiridol in a human colon carcinoma cell line involves up-regulation of the telomerase catalytic subunit and telomere elongation. Sensitivity of resistant cells to combination treatment with a telomerase inhibitorToluidinesulfonamide hypoxia-induced factor 1 inhibitors: alleviating drug-drug interactions through use of PubChem data and comparative molecular field analysis guided synthesis.Telomerase inhibitors in cancer therapy: current status and future directions.The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function.Synthesis and evaluation of analogues of 10H-indolo[3,2-b]quinoline as G-quadruplex stabilising ligands and potential inhibitors of the enzyme telomerase.Synthesis, biophysical and biological evaluation of 3,6-bis-amidoacridines with extended 9-anilino substituents as potent G-quadruplex-binding telomerase inhibitors.Natural and synthetic G-quadruplex interactive berberine derivatives.
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description
researcher
@en
wetenschapper
@nl
name
Christoph M Schultes
@en
Christoph M Schultes
@nl
type
label
Christoph M Schultes
@en
Christoph M Schultes
@nl
prefLabel
Christoph M Schultes
@en
Christoph M Schultes
@nl
P106
P31
P496
0000-0001-8478-9739