Natural and synthetic G-quadruplex interactive berberine derivatives.
about
The crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1Structure and stability of human telomeric G-quadruplex with preclinical 9-amino acridinesQuadruplex ligands may act as molecular chaperones for tetramolecular quadruplex formationBerberine enhances defects in the establishment of leaf polarity in asymmetric leaves1 and asymmetric leaves2 of Arabidopsis thaliana.Identification of novel quadruplex ligands from small molecule libraries by FRET-based high-throughput screening.Design, synthesis, and anticancer activity of novel berberine derivatives prepared via CuAAC "click" chemistry as potential anticancer agents.Polymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer.The formation and stabilization of a novel G-quadruplex in the 5'-flanking region of the relaxin gene.Polycyclic azoniahetarenes: assessing the binding parameters of complexes between unsubstituted ligands and G-quadruplex DNA.Selective repression of RET proto-oncogene in medullary thyroid carcinoma by a natural alkaloid berberine.Molecular recognition of a carboxy pyridostatin toward G-quadruplex structures: Why does it prefer RNA?Synthesis, Binding and Antiviral Properties of Potent Core-Extended Naphthalene Diimides Targeting the HIV-1 Long Terminal Repeat Promoter G-QuadruplexesMix and measure fluorescence screening for selective quadruplex binders.A hitchhiker's guide to G-quadruplex ligands.Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes.Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations.Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery?Evaluation of alkaloids binding to the parallel quadruplex structure [d(TGGGGT)]4 by electrospray ionization mass spectrometry.Design and synthesis of a berberine dimer: a fluorescent ligand with high affinity towards G-quadruplexes.New aspects of the interaction of the antibiotic coralyne with RNA: coralyne induces triple helix formation in poly(rA)*poly(rU).Aminoglycoside binding to Oxytricha nova telomeric DNA.Use of competition dialysis in the discovery of G-quadruplex selective ligands.Structural Insight into the interaction of Flavonoids with Human Telomeric Sequence8-Styryl-substituted coralyne derivatives as DNA binding fluorescent probesXanthene and xanthone derivatives as G-quadruplex stabilizing ligands.Telomerase Inhibitors from Natural Products and Their Anticancer Potential.Preliminary studies of berberine and its semi-synthetic derivatives as a promising class of multi-target anti-parkinson agents.Interactions of daidzin with intramolecular G-quadruplex.Efficient photoinduced DNA damage by coralyne.Spectroscopic, biological, and molecular modeling studies on the interactions of [Fe(III)-meloxicam] with G-quadruplex DNA and investigation of its release from bovine serum albumin (BSA) nanoparticles.Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations.Small molecule binding to a G-hairpin and a G-triplex: a new insight into anticancer drug design targeting G-rich regions
P2860
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P2860
Natural and synthetic G-quadruplex interactive berberine derivatives.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Natural and synthetic G-quadruplex interactive berberine derivatives.
@en
Natural and synthetic G-quadruplex interactive berberine derivatives.
@nl
type
label
Natural and synthetic G-quadruplex interactive berberine derivatives.
@en
Natural and synthetic G-quadruplex interactive berberine derivatives.
@nl
prefLabel
Natural and synthetic G-quadruplex interactive berberine derivatives.
@en
Natural and synthetic G-quadruplex interactive berberine derivatives.
@nl
P2093
P1476
Natural and synthetic G-quadruplex interactive berberine derivatives
@en
P2093
Anna D'Ambrosio
Armandodoriano Bianco
Giancarlo Ortaggi
Luigi Rossetti
Marco Franceschin
Maria Savino
Stefano Schirripa
Stephen Neidle
P304
P356
10.1016/J.BMCL.2005.12.001
P407
P577
2006-01-11T00:00:00Z