about
Chemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia AImproved hepatic gene transfer by using an adeno-associated virus serotype 5 vectorSafety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1.Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparationsA specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway.No detection of the retrovirus xenotropic murine leukemia virus-related virus in individuals with hemophilia.Next generation FIX muteins with FVIII-independent activity for alternative treatment of hemophilia A.Oral gene therapy for hemophilia B using chitosan-formulated FIX mutants.Factor IX variants improve gene therapy efficacy for hemophilia B.Novel hemophilia B mouse models exhibiting a range of mutations in the Factor IX gene.Factor VIII-eGFP fusion proteins with preserved functional activity for the analysis of the early secretory pathway of factor VIII.Increased prevalence of a polymorphism in the gene coding for human prothrombin in patients with coronary heart disease[Non-viral gene transfer results in therapeutic factor IX levels in haemophilia B mice][Potential of hematopoietic stem cells as the basis for generation of advanced therapy medicinal products]Transgene loss and changes in the promoter methylation status as determinants for expression duration in nonviral gene transfer for factor IX
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P50
description
researcher
@en
name
J Schüttrumpf
@en
J Schüttrumpf
@nl
type
label
J Schüttrumpf
@en
J Schüttrumpf
@nl
prefLabel
J Schüttrumpf
@en
J Schüttrumpf
@nl
P106
P31
P496
0000-0002-8855-4096