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Enantiomeric atropisomers inhibit HCV polymerase and/or HIV matrix: characterizing hindered bond rotations and target selectivityVirtual screening, docking, and dynamics of potential new inhibitors of dihydrofolate reductase from Yersinia pestis.Spruce budworm feeding and oviposition are stimulated by monoterpenes in white spruce epicuticular waxes.Discovery of a potent and selective noncovalent linear inhibitor of the hepatitis C virus NS3 protease (BI 201335).Combined directed ortho and remote metalation-Suzuki cross-coupling strategies. Efficient synthesis of heteroaryl-fused benzopyranones from biaryl O-carbamates.Tether-controlled cycloadditions for the asymmetric synthesis of decalins: increased selectivity in acetonitrile solventA modular approach to marine macrolide construction. 4. Assembly of C36-C51 and C29-C44 building blocks and evaluation of key coupling reactions targeting spongistatin 1 (altohyrtin A)Unexpected intermolecular pd-catalyzed cross-coupling reaction employing heteroaromatic carboxylic acids as coupling partnersPalladium-catalyzed decarboxylative cross-coupling reaction between heteroaromatic carboxylic acids and aryl halidesA one-pot double C-H activation palladium catalyzed route to a unique class of highly functionalized thienoisoquinolinesPalladium-catalyzed intermolecular desulfinylative cross-coupling of heteroaromatic sulfinatesSynthesis of 2,5-diaryl-substituted thiophenes as helical mimetics: towards the modulation of islet amyloid polypeptide (IAPP) amyloid fibril formation and cytotoxicityA High-Throughput Glycosyltransferase Inhibition Assay for Identifying Molecules Targeting Fucosylation in Cancer Cell-Surface ModificationApproaching the Integer-Charge Transfer Regime in Molecularly Doped Oligothiophenes by Efficient Decarboxylative Cross-Coupling
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P106
P31
P496
0000-0002-6029-2194