about
Rare missense neuronal cadherin gene (CDH2) variants in specific obsessive-compulsive disorder and Tourette disorder phenotypesFunctional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptorsHow the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems.Altered 5-HT2C receptor agonist-induced responses and 5-HT2C receptor RNA editing in the amygdala of serotonin transporter knockout mice.In a model of Batten disease, palmitoyl protein thioesterase-1 deficiency is associated with brown adipose tissue and thermoregulation abnormalities.A novel, putative gain-of-function haplotype at SLC6A4 associates with obsessive-compulsive disorder.N,N-dimethyl-thioamphetamine and methyl-thioamphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents.Human serotonin transporter gene (SLC6A4) variants: their contributions to understanding pharmacogenomic and other functional G×G and G×E differences in health and disease.Programming of Dopaminergic Neurons by Neonatal Sex Hormone Exposure: Effects on Dopamine Content and Tyrosine Hydroxylase Expression in Adult Male Rats.Mutations in monoamine oxidase (MAO) genes in mice lead to hypersensitivity to serotonin-enhancing drugs: implications for drug side effects in humansConnecting Synaptic Activity with Plasticity-Related Gene Expression: From Molecular Mechanisms to Neurological Disorders.Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneityCommon and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder.A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder.Meta-analysis of association between obsessive-compulsive disorder and the 3' region of neuronal glutamate transporter gene SLC1A1.Neurochemical and behavioral characterization of neuronal glutamate transporter EAAT3 heterozygous mice.Neonatal exposure to estradiol increases dopaminergic transmission in Nucleus Accumbens and morphine-induced conditioned place preference in adult female rats.miR-15a and miR-16 regulate serotonin transporter expression in human placental and rat brain raphe cells.Improving amphetamine therapeutic selectivity: N,N-dimethyl-MTA has dopaminergic effects and does not produce aortic contraction.Behavioral and synaptic alterations relevant to obsessive-compulsive disorder in mice with increased EAAT3 expression.3D similarities between the binding sites of monoaminergic target proteins.Dennis Luke Murphy, M.D. (1936-2017)Lack of Association between the IL6R Gene Asp358Ala Variant (rs2228145), IL-6 Plasma Levels, and Treatment Resistance in Chilean Schizophrenic Patients Treated with Clozapine
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description
investigador
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researcher
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wetenschapper
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name
Pablo R Moya
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Pablo R Moya
@nl
type
label
Pablo R Moya
@en
Pablo R Moya
@nl
prefLabel
Pablo R Moya
@en
Pablo R Moya
@nl
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P496
0000-0001-6409-1544