about
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activitySynthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors α/γ dual agonistsNew 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor α/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expressionDetermination of cymoxanil in drinking water and soil using high-performance liquid chromatography.Ligand-based chemoinformatic discovery of a novel small molecule inhibitor targeting CDC25 dual specificity phosphatases and displaying in vitro efficacy against melanoma cellsNovel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages.Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening.Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasionCDC25A and B dual-specificity phosphatase inhibitors: potential agents for cancer therapy.STAT-3 inhibitors: state of the art and new horizons for cancer treatment.Virtual screening strategies in drug discovery: a critical review.Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature.Investigational drugs targeting cyclin-dependent kinases for the treatment of cancer: an update on recent findings (2013-2016).Development of novel selective peptidomimetics containing a boronic acid moiety, targeting the 20S proteasome as anticancer agents.Identification of a new series of amides as non-covalent proteasome inhibitors.Amorfrutins are efficient modulators of peroxisome proliferator-activated receptor gamma (PPARγ) with potent antidiabetic and anticancer properties: a patent evaluation of WO2014177593 A1.Development of peptidomimetic boronates as proteasome inhibitorsDiarylheterocycle Core Ring Features Effect in Selective COX-1 InhibitionDiscovery of New Inhibitors of Cdc25B Dual Specificity Phosphatases by Structure-Based Virtual ScreeningBenzothiopyranoindole-Based Antiproliferative Agents: Synthesis, Cytotoxicity, Nucleic Acids Interaction, and Topoisomerases Inhibition PropertiesConformational switch of a flexible loop in human laminin receptor determines laminin-1 interactionStructural development studies of PPARs ligands based on tyrosine scaffold
P50
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P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Carmen Di Giovanni
@en
Carmen Di Giovanni
@nl
type
label
Carmen Di Giovanni
@en
Carmen Di Giovanni
@nl
prefLabel
Carmen Di Giovanni
@en
Carmen Di Giovanni
@nl
P31
P496
0000-0001-6950-4467