about
Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.p14ARF induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop.
P50
description
investigador
@es
researcher
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name
Tim Overkamp
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type
label
Tim Overkamp
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prefLabel
Tim Overkamp
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P31
P496
0000-0002-1612-4919