about
Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinasesRedox-linked structural changes associated with the formation of a catalytically competent form of the diheme cytochrome c peroxidase from Pseudomonas aeruginosaStructures of P. falciparum protein kinase 7 identify an activation motif and leads for inhibitor designCR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinasesN-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitineThe structure of CDK4/cyclin D3 has implications for models of CDK activationInsights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivityStructural and biochemical characterization of the Cop9 signalosome CSN5/CSN6 heterodimerStructure and function of MPN (Mpr1/Pad1 N-terminal) domain-containing proteins.Crystallization and preliminary X-ray data of a bifunctional peroxiredoxin from poplar.Assessing crystallization droplets using birefringence.An inhibitor's-eye view of the ATP-binding site of CDKs in different regulatory states.Structure and mechanism in the bacterial dihaem cytochrome c peroxidases.Recent developments in cyclin-dependent kinase biochemical and structural studies.Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex.ZOMES: the intriguing interplay of PCI complexes and the ubiquitin in protein homeostasis.Expression, purification, crystallization and preliminary characterization of uridine 5'-diphospho-N-acetylmuramoyl L-alanyl-D-glutamate:lysine ligase (MurE) from Streptococcus pneumoniae 110K/70.Crystal structure and solution NMR dynamics of a D (type II) peroxiredoxin glutaredoxin and thioredoxin dependent: a new insight into the peroxiredoxin oligomerism.The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery.Activation and catalysis of the di-heme cytochrome c peroxidase from Paracoccus pantotrophus.Crystallization and preliminary X-ray diffraction analysis of a dihaem cytochrome c peroxidase from Paracoccus denitrificans.Explicit treatment of active-site waters enhances quantum mechanical/implicit solvent scoring: Inhibition of CDK2 by new pyrazolo[1,5-a]pyrimidines.Searching for Cyclin-Dependent Kinase Inhibitors Using a New Variant of the Cope EliminationOligomeric states of the detergent-solubilized human serum paraoxonase (PON1)Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804M Kinase
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description
Lecturer in Structural Biology of Cancer-Related Targets
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name
Aude Echalier
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Aude Echalier
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type
label
Aude Echalier
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Aude Echalier
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Aude Echalier-Glazer
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Dr. Aude Echalier-Glazer
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Echalier A
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Echalier, A
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Prof. Aude Echalier
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Aude Echalier
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Aude Echalier
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aude-echalier-glazer-2b3555146