N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine

N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine

Item
http://www.wikidata.org/entity/Q27652149
Roscovitine in cancer and other diseasesSynthesis and biological evaluation of a selective N- and p/q-type calcium channel agonist.CDK/CK1 inhibitors roscovitine and CR8 downregulate amplified MYCN in neuroblastoma cells.Pharmacokinetics and biodistribution of the cyclin-dependent kinase inhibitor -CR8- in mice.Pyrazolo[1,5-a]-1,3,5-triazine as a purine bioisostere: access to potent cyclin-dependent kinase inhibitor (R)-roscovitine analogue.The cell cycle and acute kidney injury.Novel potent pharmacological cyclin-dependent kinase inhibitors.Cyclin dependent kinases in cancer: potential for therapeutic intervention.Characterization of a Pyrazolo[4,3-d]pyrimidine Inhibitor of Cyclin-Dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro.Transcriptional modulation of apoptosis regulators by roscovitine and related compounds.The effect of circadian rhythm on pharmacokinetics and metabolism of the Cdk inhibitor, roscovitine, in tumor mice model.A Simple Isomerization of the Purine Scaffold of a Kinase Inhibitor, Roscovitine, Affords a Four- to Seven-Fold Enhancement of Its Affinity for Four CDKs. Could This Be Traced Back to Conjugation-Induced Stiffenings/Loosenings of Rotational Barriers?
P2860

N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine

Item
http://www.wikidata.org/entity/Q27652149
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
N-&-N, a new class of cell dea ...... ed from the purine roscovitine
@ast
N-&-N, a new class of cell dea ...... ed from the purine roscovitine
@en
N-&-N, a new class of cell dea ...... ed from the purine roscovitine
@nl
type
label
N-&-N, a new class of cell dea ...... ed from the purine roscovitine
@ast
N-&-N, a new class of cell dea ...... ed from the purine roscovitine
@en
N-&-N, a new class of cell dea ...... ed from the purine roscovitine
@nl
prefLabel
N-&-N, a new class of cell dea ...... ed from the purine roscovitine
@ast
N-&-N, a new class of cell dea ...... ed from the purine roscovitine
@en
N-&-N, a new class of cell dea ...... ed from the purine roscovitine
@nl
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P1476
P2093
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P31
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P433
P478
P50
P577
P698
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P1433
P1476
N-&-N, a new class of cell dea ...... ed from the purine roscovitine
@en
P2093
P304
P31
P356
10.1158/1535-7163.MCT-08-0080
P433
P478
P50
P577
P698