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Q33667620-14231347-7DF8-41AE-BB28-C20674FCDD24
Q33667620-14231347-7DF8-41AE-BB28-C20674FCDD24
BestRank
Statement
http://www.wikidata.org/entity/statement/Q33667620-14231347-7DF8-41AE-BB28-C20674FCDD24
Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition.
P2860
Q33667620-14231347-7DF8-41AE-BB28-C20674FCDD24
BestRank
Statement
http://www.wikidata.org/entity/statement/Q33667620-14231347-7DF8-41AE-BB28-C20674FCDD24
rank
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type
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wasDerivedFrom
22e3641863944fec7e0bc12d2e92636c7c4297e5
P2860
Intracellular accumulation of amyloidogenic fragments of amyloid-beta precursor protein in neurons with Niemann-Pick type C defects is associated with endosomal abnormalities.