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Q34568528-2E8415BC-7DE6-4227-9F25-3E5AA85F4CF6
Q34568528-2E8415BC-7DE6-4227-9F25-3E5AA85F4CF6
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34568528-2E8415BC-7DE6-4227-9F25-3E5AA85F4CF6
Triterpenoid CDDO-Me blocks the NF-kappaB pathway by direct inhibition of IKKbeta on Cys-179.
P2860
Q34568528-2E8415BC-7DE6-4227-9F25-3E5AA85F4CF6
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34568528-2E8415BC-7DE6-4227-9F25-3E5AA85F4CF6
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type
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wasDerivedFrom
86806984fbea2e3598875454f50526ab09a318c1
P2860
A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.