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Q34921957-403D04C9-569C-4265-98DE-CE240D70FB25
Q34921957-403D04C9-569C-4265-98DE-CE240D70FB25
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34921957-403D04C9-569C-4265-98DE-CE240D70FB25
Carboxymefloquine, the major metabolite of the antimalarial drug mefloquine, induces drug-metabolizing enzyme and transporter expression by activation of pregnane X receptor.
P2860
Q34921957-403D04C9-569C-4265-98DE-CE240D70FB25
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34921957-403D04C9-569C-4265-98DE-CE240D70FB25
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wasDerivedFrom
481ab5708feabb28b0dcccce7b5340e12876f73f
P2860
A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.