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Q35685586-25051F6B-74C1-4943-9ABC-D10126DDB850
Q35685586-25051F6B-74C1-4943-9ABC-D10126DDB850
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http://www.wikidata.org/entity/statement/Q35685586-25051F6B-74C1-4943-9ABC-D10126DDB850
mTOR Complex 2 Stabilizes Mcl-1 Protein by Suppressing Its Glycogen Synthase Kinase 3-Dependent and SCF-FBXW7-Mediated Degradation.
P2860
Q35685586-25051F6B-74C1-4943-9ABC-D10126DDB850
BestRank
Statement
http://www.wikidata.org/entity/statement/Q35685586-25051F6B-74C1-4943-9ABC-D10126DDB850
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wasDerivedFrom
89bde7b4c983dd4c836dd47414aabab383e652c0
P2860
The E3 ubiquitin ligases β-TrCP and FBXW7 cooperatively mediates GSK3-dependent Mcl-1 degradation induced by the Akt inhibitor API-1, resulting in apoptosis.