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Q36633152-5828B6C9-48C7-4A72-882F-96A2130CA9EE
Q36633152-5828B6C9-48C7-4A72-882F-96A2130CA9EE
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Statement
http://www.wikidata.org/entity/statement/Q36633152-5828B6C9-48C7-4A72-882F-96A2130CA9EE
Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity.
P2860
Q36633152-5828B6C9-48C7-4A72-882F-96A2130CA9EE
BestRank
Statement
http://www.wikidata.org/entity/statement/Q36633152-5828B6C9-48C7-4A72-882F-96A2130CA9EE
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wasDerivedFrom
72c6e320827ffc2e8b6c3e6e0ed80851b1c5ea1f
P2860
The DNA polymerase gamma Y955C disease variant associated with PEO and parkinsonism mediates the incorporation and translesion synthesis opposite 7,8-dihydro-8-oxo-2'-deoxyguanosine.